Some Immunological and Genetic Aspects of the Development of Traumatic Osteomyelitis: a Review of the Literature

Abstract

This review summarizes features of the pathophysiological course of post-traumatic osteomyelitis. Options for the development of traumatic osteomyelitis in patients with immunological and genetic predispositions are considered. Along with a description of the pathophysiology and conditions for the occurrence of these processes, the features of the pathophysiological course of this disease are described in detail.Molecular genetic studies devoted to the search for an association between polymorphic gene variants and the development of chronic traumatic osteomyelitis are not sufficiently reflected in domestic and foreign literature, which confirms the relevance of this work.Key words: traumatic osteomyelitis, pathophysiology, predisposition, molecular genetic studies