Some health aspects of infections in oil and emulsions

Hill, E.C.; Al-Zubaidy, T S

doi:10.1016/0301-679x(79)90177-4

Cited by 15 publications

(10 citation statements)

References 5 publications

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“…This is a noteworthy finding because the water-based fluids are subject to high levels of microbial contamination, including endotoxin-producing gram-negative bacteria, and the inhalation of endotoxin has been hypothesized to exert a protective effect against lung cancer. Gram-negative bacteria (Pseudomonas) have been reported in machining fluids at concentrations as high as 108 colony-forming units per milliliter of fluid (25), and in the present study endotoxins were detected in samples of fluid taken at the work sites under investigation (unpublished data). Enterline et al (26) have proposed that the consistent deficit of lung cancer among workers exposed to cotton dust may be due to endotoxins, which may inhibit the growth of malignant cells in the lungs by stimulating macrophage activity, by inducing interferon release, by mitogen activity, or by inducing tumor necrosis factor.…”

mentioning

confidence: 74%

Mortality studies of machining-fluid exposure in the automobile industry. II. Risks associated with specific fluid types.

Tolbert¹,

Eisen²,

Pothier³

et al. 1992

Scand J Work Environ Health

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confidence: 74%

Mortality studies of machining-fluid exposure in the automobile industry. II. Risks associated with specific fluid types.

Tolbert¹,

Eisen²,

Pothier³

et al. 1992

Scand J Work Environ Health

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“…Although little is known about the factors that can cause the development of sinusitis in MWF-exposed workers, several researchers have suggested that some respiratory health effects seen in MWF mist exposed workers may be related to contaminating microorganisms, or their byproducts (such as endotoxins, exotoins, and mycotoxins) [16][17][18][19] . Community based studies and case studies have indicated that fungi or bacteria is one of the most important causes of allergic diseases such as bronchial asthma, allergic rhinitis and sinusitis [4][5][6][7][8][9][10] .…”

Section: Discussionmentioning

confidence: 99%

Exposure Assessment to Suggest the Cause of Sinusitis Developed in Grinding Operations Utilizing Soluble Metalworking Fluids

Park

Choi²,

Kim³

et al. 2005

Journal of Occupational Health

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Exposure Assessment to Suggest the Cause of Sinusitis Developed in GrindingOperations Utilizing Soluble Metalworking Fluids: Donguk PARK et al. Korea National Open University, Korea-A worker who ground the inner parts of camshafts for automobile engines using water-soluble metalworking fluid (MWF) for 14 yr was diagnosed with sinusitis. We postulated that the cause of sinusitis might be associated with exposure to microbes contaminating the water-soluble MWF used in the grinding operation. To uncover responsible agents for this case of sinusitis, a quantitative exposure assessment for chemical and biological agents was made and prevalence of work-related respiratory symptoms was investigated by questionnaire. The exposure ranges of MWF mist (0.59 mg/m 3 to 2.12 mg/ m 3 ) measured during grinding exceeded 0.5 mg/m 3 of the recommended exposure limit (REL). Grinders' exposures to bacteria, fungi and endotoxins were also generally higher than not only the proposed standards, but also those reported by several studies investigating the causes of respiratory effects. Statistical tests indicated that the prevalence rate of reported symptoms related to nasal cavities showed no significant differences among the operations. Evaluation of grinding operation characteristics and the quantitative exposure assessment indicated that repeated exposure to MWF mist, including water-soluble MWF contaminated with microbes may cause respiratory diseases like sinusitis or at least increase susceptibility to the development of sinusitis. Further study is underway to identify environmental risk factors for sinusitis by analyzing the relationship between medical examination results and plant characteristics including exposure data. (J Occup Health 2005; 47: 319-326)

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“…. , , , , TT .,i ,r>o-, o i i and Al-Zubaidy, 1979;Hill, 1983;Kennedy et al, cessing characteristics (Hill, 1983;Salmeen et al, ,""" , , ^ , " . . ; Mattsby-Baltzer et al, 1989a;Gordon et al, 1992;Robins et al, 1997;Smid et al, 1992).…”

Section: Introductionmentioning

confidence: 99%

“…MWF that have high concentrations of Gram-negative bacteria have been shown to have high concentrations of endotoxin (Bennett, 1972;Milton and Johnson, 1995;Rossmoore and Rossmoore, 1980). They may be an etiologic agent in the deterioration in respiratory health of workers exposed to MWF (Holdom, 1976;Hill and Al-Zubaidy, 1979;Kennedy et al, 1989;Sprince et al, 1997).…”

Section: Introductionmentioning

confidence: 99%

A Model for Predicting Endotoxin Concentrations in Metalworking Fluid Sumps in Small Machine Shops

Park

Teschke

Bartlett

2001

The Annals of Occupational Hygiene

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Methods: In British Columbia, Canada, nineteen small machine shops which used waterbased metalworking fluids (MWF) were examined. One bulk MWF sample was taken from each independent sump (/V=140) and tested for endotoxin using the Limulus Amoebocyte Lysate assay. Factors that might influence the MWF sump endotoxin concentration were investigated using mixed effect multiple regression modelling to control for repeated measures within shops.Results: The geometric mean (GM) endotoxin concentration was 6791 EU/ml. Contamination of MWF with tramp oil, MWF pH, MWF temperature, and MWF type were significant predictors of sump fluid endotoxin concentration (model P=0.0001, ordinary least squares R 2 =0.36). Concentrations of endotoxin in sump fluids were increased by MWF contamination with tramp oils such as hydraulic oils, preservative oils, spindle oils, slidway lubricants, gear lubricants, and greases (model predicted GM=17 400 EU/ml vs. 1600 EU/ml without tramp oil). Concentrations were also elevated where pH was lower than 8.5 (predicted GM=10 600, vs 3600 EU/ml for pH 8.5 to 9.5), where soluble fluids were used (predicted GM=11 800 vs. 2800 EU/ml for synthetic fluids), and where sump fluid temperatures were higher (predicted GM=2600 EU/ml at 11°C vs. 21 500 EU/ml at 32°C). The within-shop correlation of sump bulk fluid endotoxin concentrations was 38%.Conclusions: Minimizing tramp oil contamination, using synthetic fluids, and monitoring pH and temperature would be valuable tools for controlling endotoxin contamination in MWF sumps. In addition, since there was correlation within-shop, contamination of one sump in a shop may suggest changing the fluids in all.

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Some health aspects of infections in oil and emulsions

Cited by 15 publications

References 5 publications

Mortality studies of machining-fluid exposure in the automobile industry. II. Risks associated with specific fluid types.

Mortality studies of machining-fluid exposure in the automobile industry. II. Risks associated with specific fluid types.

Exposure Assessment to Suggest the Cause of Sinusitis Developed in Grinding Operations Utilizing Soluble Metalworking Fluids

A Model for Predicting Endotoxin Concentrations in Metalworking Fluid Sumps in Small Machine Shops

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