Some Effects of Dexamethasone on Nucleic Acid Metabolism in Skin of Merino Sheep

Panaretto, BA; Leish, Z.; Donnelly, J. B.

doi:10.1071/bi9820579

Cited by 1 publication

(2 citation statements)

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“…Indirect support for such an interaction is provided by the use of exogenous corticosteroids as experi-A . FOLDES AND OTHERS mental depilating agents because of their known decreasing effect of depilation force (Panaretto et al 1982;Foldes et al 1982). The known correlations between corticosteroids and skin thickness (Chapman & Bassett, 1970;Gordon 1981), between skin thickness and wool follicle depth (Chapman, Panaretto & Frith, 1982) and between follicle depth and depilation force (Gordon, 1980) may suggest a possible association between the strength of attachment of the staples and endogenous cortisol levels.…”

Section: Discussionmentioning

confidence: 99%

“…Circadian rhythms in plasma concentrations of an endogenous corticosteroid hormone, cortisol are also reported, because exogenous corticosteroids are used as experimental defleecing agents because of their potent effect on depilation force (Panaretto, Leish & Donnelly, 1982;Foldes et al 1982). The adrenal cortex and hence endogenous corticoids are also known to influence wool growth and fleece characteristics (Lindner &Ferguson, 1956).…”

Section: Introductionmentioning

confidence: 99%

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Circadian rhythm in wool depilation force in Merino and Merino X Border Leicester sheep

et al. 1985

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As part of an ongoing investigation of ovine neuroendocrine mechanisms relating to photoperiod and eventually to wool growth, the diurnal variation of depilation force (an index of the strength of attachment of wool fibres to the skin of sheep) was investigated in Merino wethers and Border Leicester Merino ewes. Circadian rhythms were demonstrated in depilation force in both ewes and wethers. Further experiments were performed to investigate circadian endocrine rhythms which may have some bearing on the observed rhythm in depilation force. Circadian rhythms 180° out of phase with the depilation force rhythm were observed in plasma cortisol concentrations and in pineal serotonin N-acetyltransferase activities in Merino wethers.

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