Editorial on the Research Topic Interaction between macroscopic quantum systems and gravityThe study of quantum macroscopic systems is an highly developed field in physics, with a huge potential for integration across different disciplines and research areas. One of the most intriguing potentiality is the analysis of the possible mutual interaction between macroscopic, coherent matter states (like superconductors and superfluids) and the local gravitational field. This fully interdisciplinary research field has witnessed a conspicuous progress in the last decades [1,4,8,10,11,13,15,22,25], and yet several questions are still completely open.This Research Topic brings together contributions analysing the interaction between gravity and materials in the superconducting state, investigating possible observable effects not explained in terms of classical physics. A deeper understanding of this unconventional interplay would lead to a noteworthy development in theoretical physics, as well as opening remarkable perspectives for future direct applications.In the research article Measurement of Anomalous Forces from a Cooper-Pair Current in High-T c Superconductors with Nano-Newton Precision, Tajmar et al. report the results of precision measurements performed with a new custom-built double pendulum thrust balance, able to detect forces down to a level of 25-100 nN. Their aim is to test whether a superconductor carrying a supercurrent is subject to anomalous forces called "framedragging" forces or recoil forces, as observed in earlier experiments [20,21]. The main virtue of the experimental setup, besides its precision, is that the entire apparatus (superconductor, cooling devices, power source) is mounted on a platform, whose motion is accurately monitored through laser interferometers. Special care has been devoted to the elimination of magnetic artifacts. The currents tested have intensity up to 15 A and are stationary, except for sharp gradients at switch-on/off. The obtained results rule out the occurrence of anomalous forces above a ratio of approximately 5 • 10 -9 N/A.