Some cardiovascular effects of the aqueous extract of the leaves of Starchytarpheta jamaicensis L. (Vahl)

Idu, MacDonald; Omogbai, Eric K. I.; ., F. Amaechina; ., J.E. Ataman

doi:10.1055/s-2006-949860

Cited by 7 publications

(10 citation statements)

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“…[9] Stachytarpheta cayennensis has been reported to be antiinflammtory, antinociceptive, anti ulcerogenic,[81011] antidiarrheoal[12] as well as sedative[13] and hypotensive. [14] An insignificant in vitro antiplasmodial activity has been reported of the plant in Peru. [5] The aim of the present study was to evaluate the in vivo antiplasmodial potential of Stachytarpheta cayennensis considering its wide acceptability as malarial remedy in southern Nigeria.…”

Section: Introductionmentioning

confidence: 99%

In vivo antimalarial activity of ethanolic leaf extract of Stachytarpheta cayennensis

2008

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Objective:To evaluate the in vivo antiplasmodial activity of the ethanol leaf extract of Stachytarpheta cayennensis in the treatment of various ailment in Niger Delta region of Nigeria, in Plasmodium berghei infected mice.Materials and Methods:The ethanolic leaf extract of Stachytarpheta cayennensis (90-270 mg/kg/day) was screened for blood schizonticidal activity against chloroquine sensitive Plasmodium berghei berghei in mice. The schizonticidal effect during early and established infections was investigated.Result:Stachytarpheta cayennensis (90-270 mg/kg/day) exhibited significant (P< 0.05) blood schizonticidal activity both in 4-day early infection test and in established infection with a considerable mean survival time comparable to that of the standard drug, chloroquine, 5 mg/kg/day.Conclusion:The leaf extract possesses significant (P< 0.05) antiplasmodial activity which confirms it's use in folkloric medicine in the treatment of malaria.

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Section: Introductionmentioning

confidence: 99%

In vivo antimalarial activity of ethanolic leaf extract of Stachytarpheta cayennensis

2008

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“…Obat-obatan ini penting karena dianggap tidak memberikan efek samping. Saat ini, penelitian difokuskan pada pemanfaatan tumbuhan obat dalam berbagai sistem tradisional (Idu et al, 2006).…”

Section: Pendahuluanunclassified

Uji Antimikroba Fraksi Ekstrak Metanol, Etil Asetat dan n-Heksana Daun Tabar-Tabar (Costus speciosus) dan Toksisitasnya Terhadap Larva Udang

Suryanto¹,

Kelana²,

Wahyuni³

2019

Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati

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A Study on antimicrobial examination of fractions of methanol, ethyl-acetate, and n-hexane extract of tabar-tabar (Costus speciosus) leaf to bacteria (Bacillus sp., Staphylococcus aureus, Escherichia coli, and Serratia marcescens) and yeast (Candida albicans), and their toxicity to brine-shrimp (Artemia salina) larvae has been done. Examination of antimicrobial activities to the microbes were done by agar diffusion method, while test for toxicity was done by exposing 2 days-old larvae to certain concentration of the extract. Preliminary tests on phytochemical compounds in leaf were done by Mayer’s, FeCl3, Mg-HCl, foam, and 10% NaOH in methanol tests. The results showed that methanol leaf extract of tabar-tabar in general inhibited more in the growth of gram-positive Bacillus sp. and S. aureus rather than to other tested microbes. Compared to methanol and ethyl-acetate fraction, n-hexane fraction of the leaf inhibited more Bacillus sp. and E. coli. Interestingly, C. albicans was highly inhibited by n-hexane fractions. LC50 of methanol extract, ethyl-acetate, and n-hexane fraction, were 45.53, 478.37, and 824.20 ppm, respectively. Preliminary test on phytochemical compounds showed saponin was only detected in fractions of methanol and ethyl acetate extracts, steroid was detected in fraction of methanol, while triterpenoid was detected in fraction of n-hexane extract. Phenolic was detected in all extract fractions, while flavonoid, kumarin, and alkaloid on the other hand were not detected.

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“…Starchytarpeta jamaicensis (L.) Vahl (Verbanaceae) popularly called Gervao, Brazillian tea and Bastard vervain is used extensively by indigenous people throughout the Amazons and tropical countries for the treatment of various ailments with a wide range of uses in ethnomedicinal practice. The plant has been reported to have reasonable antimicrobial and insecticidal properties [4]. Previous laboratory studies have verified its longstanding use in the treatment of gastrointestinal tract, and cardiovascular disorders.…”

Section: Introductionmentioning

confidence: 99%

<i>In vitro</i> inhibitory effect of methanol leaf extract of <i>Stachytarpheta jamaicensis</i> (Verbenaceae) on nonpregnant rat uterus

Amaechina¹,

Bafor²

2017

Trop. J. Pharm Res

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Purpose: To investigate the effect of the methanol extract of the plant, Stachytarpheta jamaicensis (Verbenaceae) (SJ) on uterine smooth muscles of non-pregnant female rats, with the aim of examining the oxytocic or otherwise effect of the extract. Methods: In the first phase of experiments, the effects of SJ (0.41 and 4.01 mg/ml) on oxytocin (OT) induced uterine contractions were determined and repeated after addition of salbutamol (SBL) (41.7 nM). In the second phase, verapamil (VER) (2.03 μM), SBL (41.7 nM), and SJ (0.41 and 4.01 mg/ml) were applied to the tissues after pre-contraction with K+ (80 mM). In the third phase, the effects of VER, SBL, and SJ on CaCl2-induced contractions (0.03-10.83 mM) were examined. In the fourth and final phases, the second phase experiments were repeated in a calcium-free medium and in the absence and presence of propranolol (1.54 mM) respectively. Results: SJ exhibited significant inhibitory effects on OT and CaCl2 induced uterine contractions (p < 0.05

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Some cardiovascular effects of the aqueous extract of the leaves of Starchytarpheta jamaicensis L. (Vahl)

Cited by 7 publications

References 0 publications

In vivo antimalarial activity of ethanolic leaf extract of Stachytarpheta cayennensis

In vivo antimalarial activity of ethanolic leaf extract of Stachytarpheta cayennensis

Uji Antimikroba Fraksi Ekstrak Metanol, Etil Asetat dan n-Heksana Daun Tabar-Tabar (Costus speciosus) dan Toksisitasnya Terhadap Larva Udang

<i>In vitro</i> inhibitory effect of methanol leaf extract of <i>Stachytarpheta jamaicensis</i> (Verbenaceae) on nonpregnant rat uterus

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