1999
DOI: 10.1051/epjap:1999144
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Some biomedical applications of ferrofluids

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Cited by 154 publications
(98 citation statements)
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“…Superparamagnetic, small size and low toxicity nanoparticles (NPs) of magnetite (Fe 3 O 4 ) are very versatile systems with multiple applications in science and technology [1]. Some of them were reviewed recently and include magnetic storage media [2], biosensing applications [3], medical applications such as targeted drug delivery [4], contrast agents in magnetic resonance imaging [5,6] and magnetic inks for ink-jet printing [7].…”
Section: Introductionmentioning
confidence: 99%
“…Superparamagnetic, small size and low toxicity nanoparticles (NPs) of magnetite (Fe 3 O 4 ) are very versatile systems with multiple applications in science and technology [1]. Some of them were reviewed recently and include magnetic storage media [2], biosensing applications [3], medical applications such as targeted drug delivery [4], contrast agents in magnetic resonance imaging [5,6] and magnetic inks for ink-jet printing [7].…”
Section: Introductionmentioning
confidence: 99%
“…In vitro applications such as separation, purification, and immunoassay methods rely on coating magnetic particles with proteins or monoclonal antibodies which endow the particles with the ability to bind to the specific cancer cell, DNA fragment, or enzyme of interest and remove that entity from the fluid upon application of a magnetic field (2)(3)(4). In vivo, small magnetite particles enhance image contrast in magnetic resonance methods (MRI) (5, 6) magnetic fields guide magnetic particles with attached anticancer drugs toward tumors (7), and high frequency magnetic fields heat up magnetic particles attached to a tumor, destroying the tumor tissue ("intercellular hyperthermia") (8).…”
Section: Introductionmentioning
confidence: 99%
“…Simple methods for "encapsulating" magnetic particles coat them with biocompatible surfactants (15) or coat them with a layer of adsorbed or grafted biocompatible polymer (3,6). Alternatively, loading magnetic particles into the interior of lipid vesicles creates magnetic vesicles (16).…”
Section: Introductionmentioning
confidence: 99%
“…At last, one can imagine potentialities of these superparamagnetic micelles and vesicles related to the specific properties of magnetic iron oxide in the fields of biomedicine and biotechnology: e.g., manipulation by an external magnetic field gradient, radio-frequency heating for cancer therapy, [38] and labeling of organs in magnetic resonant imaging. [39] Due to their small dimensions, these objects are potential candidates for intravenous injection.…”
Section: Magnetic Nanocomposite Micelles and Vesiclesmentioning
confidence: 99%