“…The subsequent research and development in the field has been truly phenomenal, with a vast litera ture spreading throughout medical reviews (58) and monographs (38,107,139), cosmetic and phar macy texts and reporls (4,25,47,76,77,99,154,158,164), foreign articles (54), the patent files (30), and still much remains as hiclden data within the com panies themselves. To date, the mos!…”