Some aspects of reduced quinoline chemistry

Abstract

Different synthetic paths that produce the reduced quinoline cycle are discussed: among them intramolecular cyclization, intra‐ and inter [4+2] cycloaddition reactions and other methods. Some chemical properties of tetrahydroquinolines are also analyzed.

Simple Preparation of New Potential Bioactive Nitrogen-Containing Molecules and Their Spectroscopy Analysis

“…These heterocycles play a key role in heterocyclic and medicinal chemistry. Their syntheses by various methodologies have been published extensively (Kouznetsov et al, 2005;Kouznetsov et al, 1998;Katrizky et al, 1996;Jones, 1984).…”

1,4-Dihydro-4-(nitromethyl)-2-phenyl-1-tosylquinoline-3-carbaldehyde

“…Hydroquinoline is structurally essential unit in biologically active natural products [1,2]. The hydroquinoline is widely used as a pharmacophore in drug discovery and exhibits a broad range of biological activities such as anti-HIV, antibacterial, antifungal, antimalarial, antitumor, and cardiovascular effects [3][4][5].…”

Transformations of schiff bases derived from quinoline‐8‐carbaldehyde. Synthesis of C‐8 substituted quinolines

“…Diverse substituted quinolines have been synthesized for a wide range of industrial, pharmaceutical, and biological purposes [1,2]. Likewise, 4-thiazolidinones have shown many useful applications.…”