Some Aspects of Carbohydrate Metabolism in Pregnancy With Special Reference to the Energy Metabolism and Hormonal Status of the Infant of the Diabetic Woman and the Diabetogenic Effect of Pregnancy

Baird, J. D.

doi:10.1677/joe.0.0440139

Cited by 26 publications

(5 citation statements)

References 121 publications

(150 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As a result, the fetus grows in a hyperinsulinemic and hyper- glycemic environment that leads to macrosomia and thus a higher risk of being born LGA. 26 However, in our study, antipsychotic use was associated with higher risks of gestational diabetes and of being SGA for birth weight instead. This counterintuitive observation may be the result of a more direct pharmacological insulin resistance-promoting effect by the antipsychotics.…”

Section: Commentcontrasting

confidence: 67%

Antipsychotics During Pregnancy

Bodén¹,

Lundgren²,

Brandt³

et al. 2012

Arch Gen Psychiatry

116

View full text Add to dashboard Cite

show abstract

Section: Commentcontrasting

confidence: 67%

Antipsychotics During Pregnancy

Bodén¹,

Lundgren²,

Brandt³

et al. 2012

Arch Gen Psychiatry

116

View full text Add to dashboard Cite

show abstract

“…However, a recent study suggests that there might be an association between schizophrenia and excessive fetal growth [ 11 ]. A higher risk of large-for-gestational-age has been found in mothers with schizophrenia [ 11 ], which might be due to in utero exposure to atypical antipsychotics [ 32 ] and the predisposition of women with schizophrenia to metabolic syndrome and metabolic abnormalities such as preconception diabetes or gestational diabetes [ 11 , 33 – 36 ].This finding concerning excessive fetal growth among offspring of women with affective psychosis deserves to be investigated in future research, and possible mechanisms should be explored. Further, there may be merits to studying whether maternal psychosis is associated with increased long-term risk of metabolic syndrome in offspring.…”

Section: Discussionmentioning

confidence: 99%

Adverse obstetric and neonatal outcomes complicated by psychosis among pregnant women in the United States

Zhong

Gelaye

Fricchione

et al. 2018

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

BackgroundAdverse obstetric and neonatal outcomes among women with psychosis, particularly affective psychosis, has rarely been studied at the population level. We aimed to assess the risk of adverse obstetric and neonatal outcomes among women with psychosis (schizophrenia, affective psychosis, and other psychoses).MethodsFrom the 2007 – 2012 National (Nationwide) Inpatient Sample, 23,507,597 delivery hospitalizations were identified. From the same hospitalization, International Classification of Diseases diagnosis codes were used to identify maternal psychosis and outcomes. Adjusted odds ratios (aOR) and 95% confidence intervals (CI) were obtained using logistic regression.ResultsThe prevalence of psychosis at delivery was 698.76 per 100,000 hospitalizations. After adjusting for sociodemographic characteristics, smoking, alcohol/substance abuse, and pregnancy-related hypertension, women with psychosis were at a heightened risk for cesarean delivery (aOR = 1.26; 95% CI: 1.23 - 1.29), induced labor (aOR = 1.05; 95% CI: 1.02 - 1.09), antepartum hemorrhage (aOR = 1.22; 95% CI: 1.14 - 1.31), placental abruption (aOR = 1.22; 95% CI: 1.13 - 1.32), postpartum hemorrhage (aOR = 1.18; 95% CI: 1.10 - 1.27), premature delivery (aOR = 1.40; 95% CI: 1.36 - 1.46), stillbirth (aOR = 1.37; 95% CI: 1.23 - 1.53), premature rupture of membranes (aOR = 1.22; 95% CI: 1.15 - 1.29), fetal abnormalities (aOR = 1.49; 95% CI: 1.38 - 1.61), poor fetal growth (aOR = 1.26; 95% CI: 1.19 - 1.34), and fetal distress (aOR = 1.14; 95% CI: 1.10 - 1.18). Maternal death during hospitalizations (aOR = 1.00; 95% CI: 0.30 - 3.31) and excessive fetal growth (aOR = 1.06; 95% CI: 0.98 - 1.14) were not statistically significantly associated with psychosis.ConclusionsPregnant women with psychosis have elevated risk of several adverse obstetric and neonatal outcomes. Efforts to identify and manage pregnancies complicated by psychosis may contribute to improved outcomes.Electronic supplementary materialThe online version of this article (10.1186/s12884-018-1750-0) contains supplementary material, which is available to authorized users.

show abstract

“…The increased growth rate in utero is thought to result largely from the maternal and concomitant fetal hyperglycaemia (Cornblath & Schwartz, 1966;Pedersen, 1967;Baird, 1969;Adam, 1971). When the blood glucose is closely controlled the birth weight of infants born to diabetic mothers appears to be reduced (Oakley, 1965;Essex, Pyke, Watkins, Brudenell & Gamsu, 1973;Persson, 1974).…”

Section: Maternal Metabolism and Fetal Growthmentioning

confidence: 99%

Fetal metabolism and fetal growth

Jones¹

1976

Reproduction

View full text Add to dashboard Cite

Some Aspects of Carbohydrate Metabolism in Pregnancy With Special Reference to the Energy Metabolism and Hormonal Status of the Infant of the Diabetic Woman and the Diabetogenic Effect of Pregnancy

Cited by 26 publications

References 121 publications

Antipsychotics During Pregnancy

Antipsychotics During Pregnancy

Adverse obstetric and neonatal outcomes complicated by psychosis among pregnant women in the United States

Fetal metabolism and fetal growth

Contact Info

Product

Resources

About