“…Since somatostatin can inhibit both presynaptic and postsynaptic sites, it may then directly modulate mitral cell‐granule cell synaptic interactions, and consequently alter the resulting oscillatory dynamics (Lagier et al,2004). The EPL is also innervated by feedback centrifugal fibers, including cholinergic, serotoninergic, or noradrenergic inputs (Shipley and Ennis,1996; Shepherd,2004) and somatostatin is known to influence monoaminergic release in many brain regions (Garcia‐Sevilla et al,1978; Göthert,1980; Tanaka and Tsujimoto,1981; Beal and Martin,1984; Vécsei et al,1990; Hathway et al,1998). Since peptides can act on synapses distant from their release sites, a putative action of somatostatin on such neuromodulatory elements cannot be ruled out.…”