Somatostatin immunoneutralization affects plasma metabolite concentrations in the domestic fowl

Hall, T.R.; Cheung, Any; Harvey, S.; Lam, Sau Kuen; Spencer, G. S. G.

doi:10.1016/0300-9629(86)90435-4

Cited by 10 publications

(2 citation statements)

References 28 publications

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“…Similar localization of cGLP1R has been observed in the pancreatic islets of other avian species, northern bobwhites, and common ostriches (Watanabe et al, 2018). Hall et al (1986) demonstrated a rapid increase in plasma glucose concentration after the intravenous injection of anti-somatostatin serum in domestic fowls. Overall, these observations suggest that GLP-1 in avian species may exert its physiological action on the regulation of plasma glucose concentration via somatostatin from pancreatic D cells.…”

Section: Glp-1 Secretion From Chicken L Cellssupporting

confidence: 72%

Chicken Intestinal L Cells and Glucagon-like Peptide-1 Secretion

Hiramatsu

2020

J. Poult. Sci.

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Many types of endocrine cells have been identified in the gastroenteropancreatic system of vertebrates, which have subsequently been named with alphabet (s). L cells which secrete the glucagon-like peptide (GLP)-1 are scattered in the intestinal epithelium. This review discusses the morphological features of chicken L cells and GLP-1 secretion from intestinal L cells. L cells, identified using GLP-1 immunohistochemistry, are open-type endocrine cells that are distributed in the jejunum and ileum of chickens. GLP-1 co-localizes with GLP-2 and neurotensin in the same cells of the chicken ileum. Intestinal L cells secrete GLP-1 in response to food ingestion. Proteins and amino acids, such as lysine and methionine, in the diet trigger GLP-1 secretion from the chicken intestinal L cells. The receptor that specifically binds chicken GLP-1 is expressed in pancreatic D cells, implying that the physiological functions of chicken GLP-1 differ from its functions as an incretin in mammals.

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Section: Glp-1 Secretion From Chicken L Cellssupporting

confidence: 72%

Chicken Intestinal L Cells and Glucagon-like Peptide-1 Secretion

Hiramatsu

2020

J. Poult. Sci.

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“…In animal production, studies with cysteamine have demonstrated growth-promoting action in fish, pigs and poultry (Hall et al, 1986;Yang et al, 2005;Tse et al, 2006). Ai & Han (2002) reported that when added to the goose diets, cysteamine increased the pancreatic secretion, a fact that could be explained by the inhibition of somatostatin, which would lead to increased gastrointestinal transit and thus enhance the enzyme secretion by the pancreas and finally improve the digestive activity in geese.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of cysteamine associated with different energy patterns in diets for broiler chickens

et al. 2012

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-This experiment was conducted with the objective of evaluating cysteamine (CS) supplementation in broiler chick diets with different energy density patterns. A total of 980 chicks of the Cobb 500 strain at one day of age were allocated into 28 plots. A completely randomized design in a 2 × 2 factorial arrangement, with 7 replications, was adopted. The factors under study were the supplementation (or absence) of cysteamine (60 mg/kg and 80 mg/kg of feed in the starter and growth/finishing phases, respectively) and two patterns of apparent metabolizable energy corrected by nitrogen balance (AMEn) in the diets. The energy levels (Mcal/kg of feed) practiced in pattern 1 were 3.00; 3.10; and 3.20, and for pattern 2, they were 3.05; 3.20; and 3.30 in the starter, growth and finishing phases, respectively. The diets were on the basis of corn and soybean meal with a feeding program with three diets. Feed intake, weight gain, feed conversion, feasibility and carcass yield were evaluated. There was no interaction between the CS supplementation and AME patterns in the diet upon the performance and/or carcass characteristic evaluated. Broilers fed the diet supplemented with CS presented improved feed conversion along the rearing cycle, but feed intake and weight gain were not affected by the supplementation of CS. The highest pattern of energy density (2) provided increased weigh gain in the starter phase of rearing and better feed conversion of the birds over the whole rearing period. The carcass yield was not influenced by the cysteamine supplementation and/or energy levels studied.

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