Somatosensory neurons grown on functionalized carbon nanotube mats

Xie, Jining; Chen, Linfeng; Aatre, Kiran R.; Srivatsan, Malathi; Varadan, Vijay K.

doi:10.1088/0964-1726/15/4/n02

Cited by 27 publications

(22 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Xie and co-workers determined that MWCNT mats functionalized with carboxyl groups are a permissive substrate for rat dorsal root ganglion (DRG) neurons growth, as confirmed by scanning electron microscopy (SEM) imaging. The researchers further suggested that the functional groups act as anchoring seeds enhancing neural cells and neurite adhesion (Xie et al, 2006). …”

Section: Carbon Nanotubesmentioning

confidence: 99%

See 1 more Smart Citation

Carbon nanotube-based multi electrode arrays for neuronal interfacing: progress and prospects

Bareket¹,

Hanein²

2013

Front. Neural Circuits

129

120

View full text Add to dashboard Cite

Carbon nanotube (CNT) coatings have been demonstrated over the past several years as a promising material for neuronal interfacing applications. In particular, in the realm of neuronal implants, CNTs have major advantages owing to their unique mechanical and electrical properties. Here we review recent investigations utilizing CNTs in neuro-interfacing applications. Cell adhesion, neuronal engineering and multi electrode recordings with CNTs are described. We also highlight prospective advances in this field, in particular, progress toward flexible, bio-compatible CNT-based technology.

show abstract

Section: Carbon Nanotubesmentioning

confidence: 99%

“…It was suggested that the roughness of CNTs contributes to anchoring neural cells (Zhang et al, 2005; Xie et al, 2006; Sorkin et al, 2009). Zhang et al (2005) fabricated patterned vertical MWCNT surfaces.…”

Section: Carbon Nanotubesmentioning

confidence: 99%

Carbon nanotube-based multi electrode arrays for neuronal interfacing: progress and prospects

Bareket¹,

Hanein²

2013

Front. Neural Circuits

129

120

View full text Add to dashboard Cite

show abstract

“…The increase in the efficacy of neural signal transmission may be related to the specific properties of CNT materials such as high electrical conductivity (117). A carboxyl group-functionalized MWCNT mat deposited on a track-etch membrane is a permissive substratum for somatosensory neurons, i.e., primary cultures of dorsal root ganglion neurons (115). SEM imaging reveals obvious neurite outgrowth from the cultured neurons plated on a functionalized CNT mat and an intertwinement between the neurites and underlying CNTs (Figure 6).…”

Section: Scaffolds For Neuron Cell Culturementioning

confidence: 99%

Interfacing Carbon Nanotubes with Living Mammalian Cells and Cytotoxicity Issues

Cui

Vashist

Al‐Rubeaan

et al. 2010

Chem. Res. Toxicol.

148

108

View full text Add to dashboard Cite

The unique structures and properties of carbon nanotubes (CNTs) have attracted extensive investigations for many applications, such as those in the field of biomedical materials and devices, biosensors, drug delivery, and tissue engineering. Anticipated large-scale productions for numerous diversified applications of CNTs might adversely affect the environment and human health. For successful applications in the biomedical field, the issue of interfacing between CNTs and mammalian cells in vitro needs to be addressed before in vivo studies can be carried out systematically. We review the important studies pertaining to the internalization of CNTs into the cells and the culturing of cells on the CNT-based scaffold or support materials. The review will focus on the description of a variety of factors affecting CNT cytotoxicity: type of CNTs, impurities, lengths of CNTs, aspect ratios, dispersion, chemical modification, and assaying methods of cytotoxicity.

show abstract

“…Many other studies have demonstrated the promising applications of combining CNT nanotechnology with neurons. For example, Xie et al have observed that the oxidation of CNT mats promotes cell adhesion and neurite extension [107]. It has been also demonstrated that a precise control of neurite outgrowth and branching can be achieved using CNT substrates [108].…”

Section: Nanotechnology For Biology and Medical Applicationsmentioning

confidence: 99%

Artificial intelligence in nanotechnology

Sacha

Varona

2013

Nanotechnology

View full text Add to dashboard Cite

Esta es la versión de autor del artículo publicado en: This is an author produced version of a paper published in: AbstractDuring the last decade there has been an increasing use of artificial intelligence tools in nanotechnology research. In this paper we review some of these efforts in the context of interpreting scanning probe microscopy, the study of biological nanosystems, the classification of material properties at the nanoscale, theoretical approaches and simulations in nanoscience, and generally in the design of nanodevices. Current trends and future perspectives in the development of nanocomputing hardware that can boost artificial intelligence based applications are also discussed.Convergence between artificial intelligence and nanotechnology can shape the path for many technological developments in the field of information sciences that will rely on new computer architectures and data representations, hybrid technologies that use biological entities and nanotechnological devices, bioengineering, neuroscience and a large variety of related disciplines.2

show abstract

Somatosensory neurons grown on functionalized carbon nanotube mats

Cited by 27 publications

References 10 publications

Carbon nanotube-based multi electrode arrays for neuronal interfacing: progress and prospects

Carbon nanotube-based multi electrode arrays for neuronal interfacing: progress and prospects

Interfacing Carbon Nanotubes with Living Mammalian Cells and Cytotoxicity Issues

Artificial intelligence in nanotechnology

Contact Info

Product

Resources

About