Somatic Cell and Sperm Cell Cytogenetics in a Patient with t(14; 21)

Tang, Yanping; Liu, Xiusheng; Liu, Yuan; Yang, Zihao; Yan, Chen; Xiong, Chengliang

doi:10.1016/s0379-4172(06)60076-0

Cited by 3 publications

(1 citation statement)

References 15 publications

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“…Reyan No. 1 dark green bitter gourd was bred by Tropical Vegetable Research Center, Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences, with vigorous growth and branching, long cone-shaped, 26-32 cm in length, 6.5-7.5 cm in diameter of fruit, fruit weight 400-500 g, 51000 kg per ha., light green rind, high quality, tolerant to heat, highly resistant to powdery mildew, suitable for the cultivation in tropical and subtropical regions [15].…”

Section: Variety Characteristicsmentioning

confidence: 99%

Efficient and Ecological Cultivation Techniques of Bitter Gourd

Yang¹,

Liu²,

Wang³

2012

AMR

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Construction of environment-friendly and resource-saving cultivation techniques is the key to sustainable development of agriculture and the ecological environment. In order to explore the efficient and ecological Hainan bitter gourd cultivation patterns, our laboratory had conducted production comparative study for two consecutive years (2010-2011) using Reyan No. 1 dark green bitter gourd. The results show that drip irrigation, balanced fertilization at different growth stages, bagging and the physical control of pest and disease are efficient and ecological cultivation measures of bitter gourd in Hainan.

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Section: Variety Characteristicsmentioning

confidence: 99%

Efficient and Ecological Cultivation Techniques of Bitter Gourd

Yang¹,

Liu²,

Wang³

2012

AMR

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Clinical Analysis of Y Chromosome Microdeletions and Chromosomal Aberrations in 1596 Male Infertility Patients of the Zhuang Ethnic Group in Guangxi

Shi,

Ma,

Huang

et al. 2024

Reprod. Sci.

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The long arm of the Y chromosome (Yq) contains many amplified and palindromic sequences that are prone to self-reorganization during spermatogenesis, and tiny submicroscopic segmental deletions in the proximal Yq are called Y chromosome microdeletions (YCM). A retrospective study was conducted on male infertility patients of Zhuang ethnicity who presented at Reproductive Medical Center of Nanning between January 2015 and May 2023. Seminal fluid was collected for standard examination. YCM were detected by using a combination of multiplex PCR and agarose gel electrophoresis. Preparation of peripheral blood chromosomes and karyotyping of chromosomes was performed. 147 cases (9.22%) of YCM were detected in 1596 male infertility patients of Zhuang ethnicity. Significant difference was found in the detection rate of YCM between the azoospermia group and the oligospermia group (P < 0.001). Of all types of YCM, the highest detection rate was AZFc (n = 83), followed by AZFb + c (n = 28). 264 cases (16.54%) of sex chromosomal aberrations were detected. The most prevalent karyotype was 47, XXY (n = 202). The detection rate of sex chromosomal aberrations in azoospermia group was higher than that in severe oligospermia group and oligospermia group, and the differences were significant (P < 0.001). 28 cases (1.57%) of autosomal aberrations and 105 cases (6.58%) of chromosomal polymorphism were identified. The current research has some limitations due to the lack of normal men as the control group but suggests that YCM and chromosomal aberrations represent key genetic factors influencing spermatogenesis in infertile males of Zhuang ethnicity in Guangxi.

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Is sperm FISH analysis still useful for Robertsonian translocations? Meiotic analysis for 23 patients and review of the literature

Martinez

Devillard

et al. 2018

Basic Clin. Androl.

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BackgroundRobertsonian translocations (RobT) are common structural chromosome rearrangements where carriers display a majority of chromosomally balanced spermatozoa from alternate segregation mode. According to some monotony observed in the rates of balanced segregation, is sperm FISH analysis obsolete for RobT carriers?MethodsRetrospective cohort research study on 23 patients analyzed in our center from 2003 to 2017 and compared to the data of 187 patients in literature from 1983 to 2017.Robertsonian translocation carriers were divided in six groups according to the chromosomes involved in the translocation: 9 patients from our center and 107 from literature carrying 45,XY,der(13;14) karyotype, 3 and 35 patients respectively with 45,XY,der(14;21), 5 and 11 patients respectively with 45,XY,der(13;15), 4 and 7 patients respectively with 45,XY,der(14;15), 1 and 4 patients respectively with 45,XY,der(13;22),and 1 and 10 patients respectively with 45,XY,der(14;22).ResultsAlternate segregation mode is predominant in our group of Robertsonian translocation carriers with 73.45% ±8.05 of balanced spermatozoa (min 50.92%; max 89.99%). These results are compliant with the data from literature for all translocations types (p > 0.05) and are consistent among the different types of Robertsonian translocations (p > 0.05) except for der(13;15) that exhibit lower balanced spermatozoa rates (p < 0.05 versus der(13;14), der(14;21), (13;21) and der(15;22)). Normozoospermic patients also display a significantly (p < 0.01) higher rate of balanced sperm cells than patients with abnormal seminograms whatever the defect implied.ConclusionsAccording to the discrepancies observed between der(13;15) and all the other Rob T carriers, the differences observed among patients presenting normal and abnormal sperm parameters and the input in genetical counselling, sperm FISH does not seem obsolete for these patients. Moreover, it seems important to collect more data for rare RobT.

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Somatic Cell and Sperm Cell Cytogenetics in a Patient with t(14; 21)

Cited by 3 publications

References 15 publications

Efficient and Ecological Cultivation Techniques of Bitter Gourd

Efficient and Ecological Cultivation Techniques of Bitter Gourd

Clinical Analysis of Y Chromosome Microdeletions and Chromosomal Aberrations in 1596 Male Infertility Patients of the Zhuang Ethnic Group in Guangxi

Is sperm FISH analysis still useful for Robertsonian translocations? Meiotic analysis for 23 patients and review of the literature

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