Somatic CDKN2A copy number variations are associated with the prognosis of esophageal squamous cell dysplasia
Zhiyuan Fan,
Jing Zhou,
Yuan Tian
et al.
Abstract:Background:
Somatic copy number variations (SCNVs) in the CDKN2A gene are among the most frequent events in the dysplasia-carcinoma sequence of esophageal squamous cell carcinoma. However, whether CDKN2A SCNVs are useful biomarkers for the risk stratification and management of patients with esophageal squamous cell dysplasia (ESCdys) is unknown. This study aimed to investigate the characteristics and prognostic value of CDKN2A SCNVs in patients with mild or moderate (m/M) ESCdys.
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