Somatic Acupoint Stimulation for Cancer‐Related Sleep Disturbance: A Systematic Review of Randomized Controlled Trials

Liu, Xianliang; Cheng, Hui Lin; Moss, Simon; Wang, Carol; Turner, Catherine; Tan, Jing‐Yu

doi:10.1155/2020/2591320

Cited by 9 publications

(15 citation statements)

References 33 publications

(103 reference statements)

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“…In acupuncture, a thin and strong metal needle is inserted into a specific anatomical part of the skin, and moxibustion is used as the burning-moxa to stimulate the acupuncture points or specific parts of the body. AM has been widely used to relieve nausea, [42][43][44] vomiting, [42][43][44] pain, [45][46][47][48] insomnia, [47,48] fatigue, [49,50] and other symptoms [51] in cancer patients. It has also been used to treat primary anxiety and depression, and its efficacy has been proven.…”

Section: Discussionmentioning

confidence: 99%

Acupuncture and moxibustion for cancer-related psychological disorders

Jiang

Liang

et al. 2022

Medicine

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Introduction:Cancer-related psychological disorders (CRPD) with high incidence are often underdiagnosed and undertreated. Although, some studies suggested that acupuncture and moxibustion (AM) are effective and safe for CRPD, lacking strong evidence, for instance, the relevant systematic review, meta-analysis, and randomized control trial (RCT) of a large sample, multicenter, makes the effects and safety remain uncertain. The aim of protocol is to evaluating the RCTs of AM for CRPD to verify the association of AM with the improvement of CRPD.Methods and analysis:Eight electric databases (4 English databases and 4 Chinese databases) will be searched from inception to Mar. 2022. There will be no restrictions on the category of the language. The RCTs of AM for CRPD unlimited to any type of cancer will be included. Depression and anxiety scores will be the primary outcome indicators. Two researchers will independently complete study selection, evaluate the risk of bias, and extract the data. The RevMan 5.2 software will be used to conduct data synthesis using the random-effects model. The weighted mean differences or standardized mean differences with 95% CIs will be used to present the results of measurement data, and the risk ratios with 95% CIs will be used to express the counting data. Additionally, we will use the Grading of Recommendations Assessment, Development, and Evaluation to assess evidence quality.Main results:The results of the meta-analysis will be presented with tables and figures.Ethics and dissemination:The results of this meta-analysis and meta-regression will be disseminated via publication in peer-reviewed journals and will be published at relevant conferences. The data to be used will not contain individual patient data; therefore, there is no need to worry about patient privacy.PROSPERO registration number:CRD42020177219.

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Section: Discussionmentioning

confidence: 99%

Acupuncture and moxibustion for cancer-related psychological disorders

Jiang

Liang

et al. 2022

Medicine

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“…The participants allocated to the true SA group will receive a 7-week self-administered SA intervention, which will be determined based on existing research evidence extracted from systematic reviews (three of which were completed by our study team, with two published33 34 and the other one under review), relevant theories (the inflammatory theory, the Yin-Yang theory and the Zang-Fu organs and meridians theory),23 24 practice standards35 36 and experts’ consensus. Eleven acupoints will be used as the therapeutic acupoints formula: Zusanli (ST36), Sanyinjiao (SP6), Taixi (KI3), Hegu (LI4), Neiguan (PC6), Shenmen (HT7), Baihui (GV20), Qihai (CV6), Guanyuan (CV4), Yintang (EX-HN3) and Taichong (LR3).…”

Section: Methods: Participants Interventions and Outcomesmentioning

confidence: 99%

Implementing an evidence-based somatic acupressure intervention in breast cancer survivors with the symptom cluster of fatigue, sleep disturbance and depression: study protocol of a phase II randomised controlled trial

et al. 2022

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IntroductionThe fatigue-sleep disturbance-depression (FSD) symptom cluster, as one of the most common symptom clusters in breast cancer (BC) survivors, can significantly decrease patients’ quality of life. Since the management of the FSD symptom cluster has been unsatisfactory with the use of pharmacological treatments alone, non-pharmacological approaches have, therefore, been recommended. Somatic acupressure (SA) is a promising approach given its potential benefits of cancer-related symptom alleviation and the convenience of self-practice. However, research evidence on using acupressure to manage the FSD symptom cluster has been limited. The proposed trial aims to examine the feasibility and preliminary effects of an evidence-based SA intervention for FSD symptom cluster management in BC survivors.Methods and analysisThis study will be a phase II randomised controlled trial with three study arms and 1:1:1 allocation. Fifty-one early-stage BC survivors who are experiencing the FSD symptom cluster will be randomly assigned to a true SA group, a sham SA group or a usual care group. All participants will receive an education booklet regarding FSD symptom cluster management advice as the usual care package. The participants in the true SA group will additionally receive a 7-week self-administered SA intervention. The participants in the sham SA group will additionally receive self-administered light acupressure at non-acupoints with the same frequency, session and duration as the true SA group. The primary outcomes will be feasibility outcomes related to subject recruitment and completion of study questionnaires and interventions. The secondary outcomes will be the effects of SA on fatigue, sleep disturbance, depression and quality of life. Descriptive statistics will be used to present all the outcomes. The secondary outcomes will be analysed using an intent-to-treat approach.Ethics and disseminationEthical approvals of this trial have been granted by the Human Research Ethics Committee at Charles Darwin University (H19017) and the Clinical Trial Ethics Committee at The Affiliated Hospital of Southwest Medical University (KY2019039). Findings from this trial will be published in peer-reviewed journals and presented at professional conferences.Trial registration numberThis trial was registered at ClinicalTrials.gov and the registration number is NCT04118140, with the stage at Recruiting.

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“…Since sleep disturbance in cancer patients is common and chronic, it is necessary to explore nonpharmacological therapy. Recently, the therapeutic effect of several nonpharmacological therapies on improving sleep disturbance in cancer patients has been reported, including cognitive intervention [21], aerobic exercise [22], and somatic acupoints stimulation [23]. e positive effect of auricular acupressure on improving sleep disturbance has been confirmed by several trials, which has the advantages of simple operation and few side effects [24][25][26].…”

Section: Introductionmentioning

confidence: 99%

Auricular Acupressure Therapy for Patients with Cancer with Sleep Disturbance: A Systematic Review and Meta-Analysis

Zhang

Yao

Zhang

2021

Evidence-Based Complementary and Alternative Medicine

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Aim. We aim to provide available synthesized evidence of the efficacy and safety of auricular acupressure for cancer patients with sleep disturbance. Methods. Randomized controlled clinical trials (RCTs) were identified from PubMed, EMBASE, Web of Science, The Cochrane Library, PsycINFO, Chinese Biomedical Database, China National Knowledge Infrastructure, Chongqing VIP, and Wanfang Data, and the search date ranged from the inception of the databases to May 2021. Literature screening and data extraction were independently performed by three researchers. The Cochrane collaboration’s tool for assessing the risk of bias was applied to evaluate the risk of bias of the RCTs included. The extracted data were analyzed using Rev-Man 5.4.1 software. Results. Nine trials involving 688 participants met the inclusion criteria and were included in the qualitative analysis; 6 trials involving 485 participants were included in the meta-analysis. Synthesized results showed that auricular acupressure had a significant effect on reducing the total Pittsburgh Sleep Quality Index (PSQI) score (MD = −3.88, 95% CI (−5.24, −2.53), P < 0.00001 ), and the scores of five PSQI components, sleep latency (MD = −0.53, 95% CI (−0.73, −0.32), P < 0.00001 ), subjective sleep quality (MD = −0.79, 95% CI (−1.05, −0.53), P < 0.00001 ), sleep duration (MD = −0.50, 95% CI (−0.69, −0.31), P < 0.0001 ), daytime dysfunction (MD = −0.53, 95% CI (−0.77, −0.29), P < 0.0001 ), and sleep disturbances (MD = −0.54, 95% CI (−0.60, −0.49), P < 0.00001 ), were also obviously decreased after the intervention of auricular acupressure. Shenmen and heart were the most commonly selected auricular acupoints, the main intervention durations ranged from 10 to 42 days, and the pressing times of auricular acupoints were 1–6 times a day, 1–5 min each time. One trial reported slight and transient pain caused by auricular acupressure, while the remaining 8 trials did not report obvious side effects. Conclusion. Auricular acupressure can significantly improve the sleep quality of cancer patients with sleep disturbance, with no obvious side effects. Rigorously designed clinical trials are necessary for the further support of the clinical application.

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Somatic Acupoint Stimulation for Cancer‐Related Sleep Disturbance: A Systematic Review of Randomized Controlled Trials

Cited by 9 publications

References 33 publications

Acupuncture and moxibustion for cancer-related psychological disorders

Acupuncture and moxibustion for cancer-related psychological disorders

Implementing an evidence-based somatic acupressure intervention in breast cancer survivors with the symptom cluster of fatigue, sleep disturbance and depression: study protocol of a phase II randomised controlled trial

Auricular Acupressure Therapy for Patients with Cancer with Sleep Disturbance: A Systematic Review and Meta-Analysis

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