Abstract:X-ray crystallography requires the growth of well-ordered, sufficiently sized protein crystals to obtain structural insights at atomic resolution. In addition to routinely performed parameter screening in vitro, protein crystallization in living cells, referred to as in cellulo crystallization, holds the possibility to grow a huge number of micron-sized protein crystals with comparable properties and of high quality in a short time [1,2]. The advantage of in cellulo crystallization is apparent: The cells grow … Show more
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