Solvent screening, optimization and kinetic parameters of the biocatalytic epoxidation reaction of β-pinene mediated by Novozym®435

Martins, Gustavo Dos Santos; Staudt, Amanda; Sutili, Felipe K.; Malafaia, Camila Rodrigues Adão; Leal, Ivana Corrêa Ramos

doi:10.1007/s10529-022-03265-8

Cited by 2 publications

(1 citation statement)

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“…Anhydrous and single-phase systems have also been investigated so as to improve the stability of the enzymes. For the anhydrous systems, urea-hydrogen peroxides [11,[15][16][17] and tert-butyl hydroperoxides [11,18] were used instead of aqueous hydrogen peroxide. Although these systems improved the stability of the enzymes, the conver-sion was on average low for urea-hydrogen peroxides and the high cost of tert-butyl hydroperoxides affected the economic potential of the system.…”

Section: Introductionmentioning

confidence: 99%

Impact of Pickering Emulsions Composition on Lipase Catalyzed Peroxyacetic Acid Synthesis

Adomi,

Drews

2024

Chemie Ingenieur Technik

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Due to the need for environmental protection and sustainability, there has been a rising need to replace the traditionally harsh oxidative functionalization process, which is essential for syntheses of various organic compounds, by biocatalysis. However, the investigated alternative processes are still challenged with enzyme instability and/or low specific reaction rate. Due to these still existing challenges and the recognition of Pickering emulsions as an efficient platform for continuous biphasic biocatalysis, the first, enzymatic step of the lipase catalyzed oxidative functionalization was investigated in bioactive Pickering emulsions. The study focused on the impact of Pickering emulsion composition such as the volume phase fraction, type and concentration of the nanoparticles and enzymes on continuous peroxyacetic acids synthesis. The type of nanoparticles used and Candida antarctica lipase B concentration significantly impacted the process while the other named parameters only had a marginal influence.

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