Solvent-preserved, bovine cancellous bone blocks used for reconstruction of thoracolumbar fractures in minimally invasive spinal surgery?first clinical results

Schultheiß, Markus; Sarkar, Michael R.; Arand, M.; Kramer, Michael D.; Wilke, Hans–Joachim; Kinzl, L.; Hartwig, E.

doi:10.1007/s00586-004-0764-7

Cited by 26 publications

(25 citation statements)

References 35 publications

(56 reference statements)

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“…with incomplete paraplegia (Frankel C): bisegmental instrumentation L1-3 with the USSä internal fixator, monosegmental anterior fusion with the Synexä a. accident, b post-operative, c after implant removal, d CT after implant removal (14 months after accident): bony integration of the Synexä 11/39 patients, by about 5-7°in nine and ‡10°in two patients. The use of bovine bone for anterior reconstruction was disappointing and let to bony integration in just 2/11 patients compared to 8/11 patients sustaining autologeous bone grafts [22].…”

Section: Discussionmentioning

confidence: 99%

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Anterior vertebral body replacement with a titanium implant of adjustable height: a prospective clinical study

et al. 2006

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Section: Discussionmentioning

confidence: 99%

“…The risk of an infection by using allografts should be almost zero now according to up-to-date recommendation. Using xenogenic bone the bony integration is not yet satisfactory [22].…”

mentioning

confidence: 99%

Anterior vertebral body replacement with a titanium implant of adjustable height: a prospective clinical study

et al. 2006

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“…Animal studies showed a proper osteointegration of the material [7], which was not reproduced in the series by Schultheiss et al where they reported delayed incorporation of bovine cancellous blocks to that of autogenous tricortical iliac crest bone grafts for reconstruction of thoracolumbar fractures [15]. One of the reasons could be that to overcome the antigenicity of xenogenous tissues, the grafts are submitted to a chemical process that ensures their biotolerance, but also reduces their osteoinductive potential.…”

Section: Discussionmentioning

confidence: 96%

“…Allografts or bone substitutes carry the risk of infection and failure to incorporate with the host bone [3]. There is however limited information on the use of xenografts [15]. With the introduction of bovine, solventpreserved cancellous bone blocks (Tutoplast bovine cancellous bone block, Tutogen, Erlangen, Germany) a European Community-certified bone material is commercially available in standardised sizes.…”

Section: Introductionmentioning

confidence: 99%

Bovine cancellous xenograft in the treatment of tibial plateau fractures in elderly patients

Bansal

Bhagat

Shukla

2008

International Orthopaedics (SICOT)

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The objective was to evaluate the efficacy of xenografts to improve the outcomes in elderly patients with tibial plateau fractures. Nineteen cases with a mean age of 74 years were followed prospectively from 1998 to 2003. Six patients each belonged to Schatzker types III, IV and V and one patient belonged to type II. Open reduction with fixation and xenograft impaction was carried out. Clinical and radiological union was assessed including infection rate, incorporation of the xenograft and average collapse of the fracture. The average union time was 20 weeks. No patient had wound infection and all had excellent incorporation of the xenograft with union. The average collapse was 4 mm on follow-up. This series shows the use of only an xenograft in acute fixation of these fractures with favourable outcome. Furthermore, it reduces operative time, bleeding and associated co-morbidities, which is of more significance in an elderly age group.

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“…The clinical outcome was promising but there was a distinct loss of correction in 11/39 patients; 5-7°in nine and C10°in two patients. The use of bovine bone for anterior reconstruction was disappointing and led to bony integration in just 2/11 patients compared to 8/11 patients sustaining autologous bone grafts [22].…”

Section: Discussionmentioning

confidence: 99%

Anterior vertebroplasty of adjacent levels after vertebral body replacement

2011

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The aim of this study was to evaluate the feasibility of a new method, which should help to avoid cage subsidence after vertebrectomy in short fusions. After implantation of an extendable vertebral body replacement (VBR) the two adjacent endplates to the fractured or destroyed vertebra were augmented with bone cement using the anterior approach in 20 patients with short circumferential fusion. All patients were followed up for 2 years clinically and radiographically. X-rays were reviewed for kyphosis, cage subsidence, presence of a solid fusion mass and instrumentation failure. Changes in every day activities (Oswestry Disability Index-ODI) and visual analogue scale (VAS), pain score, as well as techniquerelated complications were examined. The mean amount of kyphosis correction was 12.8°(±6.4°) and changed by only 0.3°(±0.4°) until last follow-up. Pain (VAS) and ODI scores were significantly improved and did not change until last follow-up. In all but two cases, the authors observed solid union with incorporation of the cage. No surgeryrelated complications were recorded. In one case revision was advised because of non-union due to septic loosening. The augmentation of the adjacent vertebras after anterior VBR provides an enhancement of the interface between cage and vertebra in cases with poor bone quality and in revision surgery. The technique is simple and safe, as the needles can be placed under visual control. Cement augmentation of the endplates may reduce interbody device subsidence.

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Solvent-preserved, bovine cancellous bone blocks used for reconstruction of thoracolumbar fractures in minimally invasive spinal surgery?first clinical results

Cited by 26 publications

References 35 publications

Anterior vertebral body replacement with a titanium implant of adjustable height: a prospective clinical study

Anterior vertebral body replacement with a titanium implant of adjustable height: a prospective clinical study

Bovine cancellous xenograft in the treatment of tibial plateau fractures in elderly patients

Anterior vertebroplasty of adjacent levels after vertebral body replacement

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