Solvent-free lipase-mediated synthesis of six-membered cyclic carbonates from trimethylolpropane and dialkyl carbonates

Ionic liquids as transesterification catalysts: applications for the synthesis of linear and cyclic organic carbonates

“…A 60% yield was achieved along with an effective recycle of the catalyst [17], ii) the formation of six-membered cyclic carbonates by the transesterification of dialkyl carbonates with trimethylolpropane. The products were achieved in high yields (85%) and used as monomers for polyurethanes and polycarbonates [18], and iii) the conversion of oils for which lipase was identified as the most suitable enzyme for an innovative and green production of biodiesel [19]. …”

Microwave assisted process intensification of lipase catalyzed transesterification of 1,2 propanediol with dimethyl carbonate for the green synthesis of propylene carbonate: Novelties of kinetics and mechanism of consecutive reactions

“…Candida antarctica lipase showed the highest TMC yield with maximum of 63% at 70°C for 6-day reaction in an organic solvent and typical ring opening polymerization of TMC was accomplished with highest conversion of 91% at 100°C in 5 days. Six-membered cyclic carbonates ($85% yield) were synthesized using lipase-catalyzed reaction of TMP with dialkylcarbonate followed by non-catalytic thermal disproportionation under solventless conditions at 80°C giving a mixture of cyclic and linear carbonates [26]. Reaction between polyol and dialkylcarbonate over Novozym 435 under different conditions has been reported [27].…”

Chlorine‐Free Synthesis of Organic Alkyl Carbonates and Five‐ and Six‐Membered Cyclic Carbonates

“…Thes yntheses were as traightforward andg reenp rocess comparedt op reviousr eports. [14,17] Thep resence of molecular sieves was shownt ob e important for the reactionb etween the alcohol/polyol and DMCe xcepti nt he case of 1,2-diols.M olecular sieves 4 serve to selectively adsorb the reactionb yproduct,m ethanol, which shifts the equilibriumt owards the product formation, and preventing the reverse reaction from taking place,b ut required at emperature much higher than the boiling point of methanol. Molecular sieves 3 and 5 are usedfor absorption of water and larger molecules (than methanol), respectively,a nd were hence not suitable for the reaction.…”

“…[17] In the presents tudy,w ed emonstrate the alkyl carbonylation of various mono-alcohols and polyols with high selectivity by reactionw ith DMC in the presence of molecular sieves and without anya dditional solvent and catalyst (Scheme1). Them ethod provides an ew facile and potentially greenr oute for carbonylation of alcohols and synthesiso fc yclic carbonates.…”