Solvent-free cyclization of linear dienes using olefin metathesis and the Thorpe-Ingold effect

Morphology control in precision polyolefins

“…Interestingly, these acid-acid correlations persist above the melt [22]. The correlations between acid dimers in the amorphous matrix result in an X-ray scattering peak, which is not observed in the random ROMP analogs, due to the fact that the dimer positions are uncorrelated.…”

“…As ring-strain in the monomer is not required, a wide variety of diene monomers is possible. ADMET has been used to produce polymers containing simple hydrocarbons [3,4], aromatic amines [5], branched acids [6,7], ethers [8,9], silanes [10], acetals [11], esters [12][13][14][15], aromatic moieties [16][17][18][19][20], thioethers [21], and ketones [14,22], to name a few.…”

Why is RCM Favoured Over Dimerisation? Predicting and Estimating Thermodynamic Effective Molarities by Solution Experiments and Electronic Structure Calculations

“…The attempted syntheses of Forbes and Wagener [31] and the oxocene forming RCMs described by Linderman et al [32] (Scheme 3) are examples of systems for which the substrate structure exerts a dramatic effect on the reaction outcome.…”

Progress in Metathesis Through Natural Product Synthesis

“…The strong dependence of RCM yields on the size of the alcohol protecting group had already been observed by Taylor et al in their approach to the oxocene core of laureatin. [47] We believe that in the case of the protected alcohol the cyclic compound 54b is more stable than the corresponding dimers, but that the opposite trend is true for the free alcohol 54a, [48] so that even if dimers are produced in the reaction of 53b, they will eventually be converted into the cyclic product 54b. This protecting group effect is even more striking for the formation of cyclooctenes: RCM of the alcohol 55a (Scheme 14) with the second-generation catalyst GN did not lead to any cyclic product, whereas the corresponding ether 55b furnished the desired compound 56b in 90 % yield.…”