Solvent extraction of amino acids into a room temperature ionic liquid with dicyclohexano-18-crown-6

Smirnova, S. V.; Torocheshnikova, I. I.; Formanovsky, A. A.; Pletnev, I. V.

doi:10.1007/s00216-003-2398-8

Cited by 150 publications

(93 citation statements)

References 38 publications

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“…Examples of different extraction systems are presented in Table 2. It should be emphasised that the extractability of acids (Matsumoto et al, 2004) and amino acids (Smirnova et al, 2004) could be enhanced by the addition of different extractants such as trin-butylphosphate or crown ether respectively to the ionic liquid phase. If analytes exist in ionic form, the extraction occurs by an ion-exchange mechanism involving transfer of appropriate ions to maintain electroneutrality.…”

Section: Liquid-liquid Extraction By Hydrophobic Ionic Liquidsmentioning

confidence: 99%

Ionic Liquids in Separation Techniques

Flieger¹,

Czajkowska-Żelazko²

2011

Applications of Ionic Liquids in Science and Technology

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Section: Liquid-liquid Extraction By Hydrophobic Ionic Liquidsmentioning

confidence: 99%

Ionic Liquids in Separation Techniques

Flieger¹,

Czajkowska-Żelazko²

2011

Applications of Ionic Liquids in Science and Technology

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“…Also, in Ref. (37), amino acids Trp, Gly, Ala, Leu were extracted efficiently from aqueous solution at pH 1.5-4.0 (Lys and Arg at pH 1.5-5.5) into the RTIL [BMIm][PF 6 ] with dicyclohexano-18-crown-6 (DC18C6). The most hydrophilic amino acids, such as Gly, were extracted as efficiently as the less hydrophilic ones (92-96%).…”

Section: Extractionmentioning

confidence: 99%

Ionic Liquids in Chemical Analysis

Koel

2005

Critical Reviews in Analytical Chemistry

328

195

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Room-temperature ionic liquids are salts with a melting point close to or below room temperature. They form liquids composed in the majority of ions. This gives these materials the potential to behave very differently when they are used as solvents compared to conventional molecular liquids. The search for their application is growing in every area of analytical chemistryelectrochemistry, chromatography, electrophoresis, and even mass spectrometry. The literature on ionic liquids is growing almost exponentially. The basis for this activity is the easy preparation of salts with different ion constituents. This ability might best be described as the "chemical tunability" of ionic liquids, a class of solvents with members possessing similar physical properties but having different chemical behavior. Their good solvating properties, together with large spectral transparency, make ionic liquids suitable solvents for spectroscopic measurements. It has been demonstrated that task-specific ionic liquids have advantages compared to common solvents used as separation media in liquid-liquid extraction processes achieving high efficiencies and selectivities of separation. The main advantage for other applications of ionic liquids in analytical chemistry lies in their low volatility which makes them useful as solvents for working in both high-temperature (gas chromatography (GC) stationary phases) and high-vacuum (MALDI matrixes) environments. When using an ionic liquid as an electrolyte medium, it is possible to achieve a broader range of operational temperatures and conditions relative to other conventional electrolytic media, and this makes ionic liquids promising materials in various electrochemical devices (e.g., batteries, fuel cells, sensors, and electrochromic windows).

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“…8 Among the various appealing applications, the use of ILs as solvents in liquid-liquid extraction processes has recently generated a great deal of excitement and seems to be particularly promissory. 9,10 In fact, the replacement of conventional organic solvents by ILs as extractors offers not only environmental advantagessenergy savings in the separation of the extracted product from the IL due to the low vapor pressure of the latest and its potential recoverability for reuse 11 sbut also the possibility of improving selective separation processes by customizing and manipulating the properties of the liquid through the modification of the anions and cations that compose them. As far as this aspect is concerned, the solvation ability of the IL and its miscibility with other solvents present in the extraction media can be dramatically altered, enabling the optimization of the efficiency of the recovery.…”

Section: Introductionmentioning

confidence: 99%

Towards an Understanding of the Mutual Solubilities of Water and Hydrophobic Ionic Liquids in the Presence of Salts: The Anion Effect

et al. 2009

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The understanding of the specific interactions between salt ions and ionic liquids (ILs) in aqueous solutions is relevant in multiple applications. The influence of a series of anions on the solubility of 1-butyl-3-methylimidazolium tricyanomethane in aqueous environment was here studied. This study aims at gathering further information to evaluate the recently proposed 1,2 mechanisms of salting-in-and salting-out-inducing ions in aqueous solutions of ILs and to provide insights at the molecular-level on the phenomena occurring in these systems. The observed effect of the inorganic species on the aqueous solubility of the ionic liquid qualitatively follows the Hofmeister series, and it is dependent on the nature and concentration of the anions. The liquid-liquid equilibrium data and 1 H NMR results here reported support a model according to which salting-in-and salting-out-inducing ions operate by essentially different mechanisms. While salting-out is an entropically driven effect resulting from the formation of hydration complexes and the increase of the surface tension of cavity formation, the salting-in phenomena is a consequence of the direct binding of the ions to the hydrophobic moieties of the IL. Further evidence here obtained suggests that the interactions of the inorganic ions are not only established with the cation of the IL, but also with the anion, with the observed solubility effect the result of a balance between those two types of interactions.

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Solvent extraction of amino acids into a room temperature ionic liquid with dicyclohexano-18-crown-6

Cited by 150 publications

References 38 publications

Ionic Liquids in Separation Techniques

Ionic Liquids in Separation Techniques

Ionic Liquids in Chemical Analysis

Towards an Understanding of the Mutual Solubilities of Water and Hydrophobic Ionic Liquids in the Presence of Salts: The Anion Effect

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