Solvent Effects on the Monobromination of α,ω-Diols:  A Convenient Preparation of ω-Bromoalkanols

Abstract

Solvent Effects on the Monobromination of α,ω-Diols: A Convenient Preparation of ω-Bromoalkanols.-Best conditions for the formation of ω-bromoalkanols are heating diols with HBr in toluene at reflux without Dean-Stark trap.

Fluoroalkene modification of mercaptoacetamide-based histone deacetylase inhibitors

“…23 Then the other hydroxyl was converted to carboxylic acids 3 by the Anelli oxidation. 24 The acids 3 were converted to acid chlorides and were treated with aniline in the presence of N-methylmorpholine to obtain benzamides 4.…”

“…27 x-Bromo alcohols 2a and 2b were prepared according to reported procedures. 23 x-Bromo carboxybenzamides 4a and 4b were prepared in accordance with the method described in the literature. 28 …”

Novel metallomesogenic polyurethanes: Synthesis, characterization and properties

“…The O-alkylation of 2,4-dihydroxy benzaldehyde was achieved by treating with 6-bromohexanol in the presence of sodium hydroxide. The 6-bromohexanol was also prepared from 1,6-hexanediol, followed by purification with column chromatography and was well characterized according to the literature procedure [33]. The alkylated product 3a was obtained as white solid, after purification by column chromatography.…”

Kinetics of 1,3-dipolar cycloaddition on the surfaces of Au nanoparticles

“…ω-Bromoalkanols were prepared from the corresponding diol [24]. All ω-bromoalkanols were subsequently converted to the ω-bromoalkane thiols according to literature procedure [25].…”