Solvent colorimetric paper-based polydiacetylene sensors from diacetylene lipids

Pumtang, Suricha; Siripornnoppakhun, Warathip; Sukwattanasinitt, Mongkol; Ajavakom, Anawat

doi:10.1016/j.jcis.2011.08.074

Cited by 61 publications

(43 citation statements)

References 41 publications

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“…14 Paper-based solid state sensors are very economical, environmentally friendly and convenient to use. [49][50][51][52][53] It is important to emphasize here that, compared with our previous uo-rophore F1, F4 not only possesses a 5 times higher quantum yield but also has a K sv value 3 times higher. 34 This new uo-rophore is thus tested for feasibility as a Cu 2+ sensor detectable by the naked eye.…”

Section: Resultsmentioning

confidence: 58%

Highly sensitive salicylic fluorophore for visual detection of picomole amounts of Cu2+

et al. 2013

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Four new fluorophores containing multiple fluorogenic branches of phenylene-ethynylene and salicylic acid Cu 2+ binding sites are synthesized and evaluated as Cu 2+ sensors in aqueous media. The fluorophore, F4, having a triphenylamine core and three fluorogenic branches, possesses superior sensitivity, selectivity and emission properties for fluorescence quenching detection of Cu 2+ . This fluorophore exhibits the highest Cu 2+ quenching sensitivity in aqueous solution; K sv ¼ 5.79 Â 10 6 M À1 .The relatively high fluorescence emission of this fluorophore provides excellent visual contrast in a solid state paper-based sensor that enables naked eye detection of Cu 2+ at the picomole level.

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Section: Resultsmentioning

confidence: 58%

Highly sensitive salicylic fluorophore for visual detection of picomole amounts of Cu2+

et al. 2013

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“…Similarly, a positive result in protein assays is interpreted from a colour change of tetrabromophenol blue from yellow to blue [70,73]. Up to date, multiplex colorimetric assays included medical diagnostics [81,87,90,91], environmental tests [76,83,84,86,89], and food quality tests [77,88] (Fig. 1.2a).…”

Section: Colorimetric Reagentsmentioning

confidence: 99%

Point-of-Care Diagnostics

Yetisen

2014

Holographic Sensors

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Rapid tests that are low-cost and portable are the first line of defence in healthcare systems. Dipstick and lateral-flow are the two universal assay formats as they are lightweight and compact, and provide qualitative results without external instrumentation. However, existing formats have limitations in the quantification of analyte concentrations. Hence, the demand for sample preparation, improved sensitivity and user-interface has challenged the commercial products. Recently, capabilities, sensors and readout devices were expanded to multiplexable assays platforms, which might transcend the capabilities of existing design format of diagnostic tests. This chapter outlines the evolution of diagnostic devices and current trends in the development of qualitative and quantitative sensing devices for applications in healthcare, veterinary medicine, environmental monitoring and food safety. The chapter also discusses design parameters for diagnostics, their functionalisation to increase the capabilities and the performance, emerging sensing platforms and readout technologies. The factors which limit the emerging rapid diagnostics to become commercial products are also discussed.The life expectancy has grown worldwide, which also increased the healthcare spending [1, 2]. For example, 720 million people will be aged 65 or older by 2020. Currently four in five people over the age of 75 take at least one prescribed medicine, and this trend is set to increase [3]. For some of the medications, large pharma find it the hard to recover R&D costs while the pressure from the regulatory agencies also increased for the use of new drugs as the first line of defence based on efficacy and cost. Hence, the global healthcare trends and ever increasing pressure from regulatory agencies put a strong case for the development of diagnostics for healthcare monitoring as well as the evaluation of drug efficacies in clinical trials. All these considerations parallels governments' and insurance companies' interests in obtaining the best performance possible and treatment benefits they support. These trends are behind the driving force for the development of diagnostics that can reduce the healthcare costs by developing effective drugs and identifying diseases and conditions at an early stage.The major stumbling block in monitoring and controlling diseases/contaminations remains delivering simple, low-cost and robust diagnostic tests [4,5]. In the developing world, the basic healthcare infrastructure and trained healthcare personnel are

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“…CPs are a class of polymers which could undergo distinct color changes under various external stimuli such as heat, oxidation or reduction, doping and de-doping, and ligand-receptor interactions, which makes them the most promising sensing materials for pollutant assay [105,106]. Interestingly, a series of PDA-embedded electrospun nanofibers are prepared by two steps: first, electrospinning the blend which contains PEO, tetraethyl orthosilicate, and several commercially available or easily obtainable diacetylene (DA) monomers and, second, polymerization of the molecular-assembled DAs to form polymer nanofibers containing embedded PDAs [107,108] (Fig.…”

Section: Colorimetric Sensorsmentioning

confidence: 99%

Electrospun Nanofiber-Based Sensors

Wang

Ding

2014

Nanostructure Science and Technology

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Monitoring of usable, explosive, and hazardous materials (gases, heavy metal ions, and organic contaminants) is one of the most important concerns that has attracted growing attention in the past few decades. Numerous sensors have been developed to meet the demands and the pursuit of highly sensitive, selective, reversible, fast response and recovery, cost-effective, and portable sensors which have gained great interest. Electrospun nanofibrous membranes that possess large surface area, high porosity, good interconnected porous structure, and flexibility of surface functionalization are expected to be ideal candidates of substrates to improve the performance of the sensors. More interestingly, the novel two-dimensional nanofiber/net membranes fabricated by electrospinning/netting are demonstrated to have extremely large surface area and unique pore structure, which could further enhance the sensitivity, stability, and response speed of the sensors. In this chapter, we summarize recent progress in the development of electrospun nanofiber-based sensors, describe the design of different types of sensors, and discuss their sensing performances in detail. This chapter might bring further development and evolution of sensors based on electrospun nanofibers for the detection of various analytes.

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Solvent colorimetric paper-based polydiacetylene sensors from diacetylene lipids

Cited by 61 publications

References 41 publications

Highly sensitive salicylic fluorophore for visual detection of picomole amounts of Cu2+

Highly sensitive salicylic fluorophore for visual detection of picomole amounts of Cu2+

Point-of-Care Diagnostics

Electrospun Nanofiber-Based Sensors

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