Solvent- and catalyst-free, quantitative protection of hydroxyl, thiol, carboxylic acid, amide and heterocyclic amino functional groups

Abstract

Various substrates are quantitatively protected by 3,4-dihydro-2H-pyran at 125 °C in the absence of any additional chemicals, without generating any waste materials.

The green Knoevenagel condensation: solvent-free condensation of benzaldehydes

“…These so-called solvent-free conditions can lead to additional improvements such as the reduced amount of catalyst needed, increased reaction rate and higher yield (13). It is believed that solvent-free organic transformations are industrially useful and fit well with the principles of Green Chemistry (14,15).…”

Thermo/pH dual-responsive micelles based on the host–guest interaction between benzimidazole-terminated graft copolymer and β-cyclodextrin-functionalized star block copolymer for smart drug delivery

“…1B3. The major resonance peaks at 7.1–7.7 ppm corresponded to benzene protons, and the chemical shift at 8.4 ppm attributed to imidazole proton were completely appeared, which showed the benzimidazole molecules were conjugated onto PHEMA- g -PCL [ 35 ]. The results proved the successful synthesis of PHEMA- g -(PCL-BM) copolymer.…”

“…The FTIR spectrum of the guest is characterized by absorption peaks at 1372 cm −1 (for C−N stretching vibration), 732 and 1190 cm −1 (for C−H vibration), 1244 cm −1 (for C−C stretching vibration) [ 35 – 37 ]. All of these peaks are induced by benzimidazole.…”

A Highly Effective Route to Si−O−Si Moieties through O‐Silylation of Silanols and Polyhedral Oligomeric Silsesquioxane Silanols with Disilazanes

“…[59] Therefore, it is highly desirable to reduce the amount of catalyst (or avoid its use), and to minimize waste generatedd uring the reaction. [63][64][65][66][67][68][69][70][71][72] Important advantages of many of thesem ethods are their simplicity and efficiency.I np articular,r oom-temperature (RT) reactions are very attractive for potential further application.G iven all this, we focusedo nd eveloping the synthesis of organosilicon compoundsi nagreen chemistry manner. [63][64][65][66][67][68][69][70][71][72] Important advantages of many of thesem ethods are their simplicity and efficiency.I np articular,r oom-temperature (RT) reactions are very attractive for potential further application.G iven all this, we focusedo nd eveloping the synthesis of organosilicon compoundsi nagreen chemistry manner.…”

“…[60][61][62] Consequently,t he development of catalyst-free synthetic procedures has received significant interesti nr ecent times. [63][64][65][66][67][68][69][70][71][72] Important advantages of many of thesem ethods are their simplicity and efficiency.I np articular,r oom-temperature (RT) reactions are very attractive for potential further application.G iven all this, we focusedo nd eveloping the synthesis of organosilicon compoundsi nagreen chemistry manner.…”