Solvatochromic sensors detect proteome aggregation in stressed liver tissues with hepatic cancer and cirrhosis

Jing, Biao; Li, Junpeng; Ke, Guo; Zeng, Lianggang; Sui, Jidong; Zhang, Zhenduo; Wang, Zhiming; Hao, Jiahu; Sun, Jianguo; Zhao, Xue; Zhao, Qian; Wan, Wang; Dong, Xuepeng

doi:10.1039/d3tb00984j

J. Mater. Chem. B

2023

DOI: 10.1039/d3tb00984j

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Solvatochromic sensors detect proteome aggregation in stressed liver tissues with hepatic cancer and cirrhosis

Biao Jing¹,

Junpeng Li²,

Guo Ke³

et al.

Abstract: Protein misfolding and aggregation invovles complex cellular processes with clinical implications in various diseases. However, detection of aggregated proteome without defined 3-D structures in complex biological milieu is challenging. This...

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Solvatochromic sensors detect proteome aggregation in stressed liver tissues with hepatic cancer and cirrhosis

Abstract: Protein misfolding and aggregation invovles complex cellular processes with clinical implications in various diseases. However, detection of aggregated proteome without defined 3-D structures in complex biological milieu is challenging. This...

Cited by 2 publications

References 44 publications

Dual-state emissive imidazo[1,2-α]pyridines with full color emission, acidochromism, viscosity-dependent fluorescence, and bioimaging applications

Dual-state emissive imidazo[1,2-α]pyridines with full color emission, acidochromism, viscosity-dependent fluorescence, and bioimaging applications

Imidazo[1,2-α]pyridine-based polarity and viscosity-dependent fluorescent probes and application in selective detection of 2,6-dichloro-4-nitroaniline

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