“…This reaction has been studied in 88% CH 3 OH-12% H 2 0 [134], in dimethylacetamide [134], in methanol [144], in ethanol [112,144], in dimethylformamide [112], dimethylacetamide (DMAC) [134], and in nitromethane [101]. At 100°C 88% MeOH-12% H 2 0 and DMAC have the same dielectric constant, but the forward reaction rate diminished by 10 4,68 (log/: changes from +1.24 to -3.44) on transfer from the dipolar aprotic solvent DMAC to the protic solvent 88% MeOH-12% H 2 0 .…”