Soluble fibre as a treatment for inflammation in asthma

RETRACTED ARTICLE: Role of the gut microbiome in chronic diseases: a narrative review

“…Children with high amounts of butyrate and propionate in feces at 1 year of age have significantly less atopic sensitization and are less likely to have asthma between 3 and 6 years [ 45 ]. In addition, soluble fiber may ameliorate the effects by exerting anti-inflammatory action via SCFAs binding to associated G-protein-coupled receptors (GPCRs) [ 46 , 47 ].…”

The effects of dietary fiber on common complications in critically ill patients; with a special focus on viral infections; a systematic reveiw

“…A negative association was reported between DF and systemic inflammation 29 . DF decreases the risk of chronic diseases through modulating inflammatory processes 30 . It was reported that improving the gastrointestinal flora through receiving DF may prevent severe inflammatory responses in patients with viral infections by maintaining the function of the immune system at the optimum level 15 .…”

“…The soluble fibers undergo degeneration by anaerobic bacteria present within the colon, resulting in the assembly of many metabolic by‐products, like SCFAs and lactate 37 . The SCFAs produced by Bifidobacteria and Lactobacilli lower luminal pH, preferentially stimulating the expansion of those classically “health‐promoting” bacteria and inhibiting the proliferation of “harmful” bacteria, including enteric pathogen Escherichia coli 30 . The soluble fibers may cause more biodiversity of the gut microbiome than insoluble fiber, which is associated with increased protection against inflammation 38 .…”

Die Rolle des Darmmikrobioms bei chronischen Krankheiten: Eine narrative Übersichtsarbeit

“…Kinder mit einem hohen fäkalen Butyrat- und Propionatgehalt im Alter von 1 Jahr haben eine deutlich geringere atopische Sensibilisierung und eine geringere Wahrscheinlichkeit, im Alter zwischen 3 und 6 Jahren an Asthma zu erkranken [45]. Darüber hinaus können lösliche Ballaststoffe die Auswirkungen verbessern, indem sie über die Bindung von SCFAs an assoziierte G-Protein-gekoppelte Rezeptoren (GPCRs) eine entzündungshemmende Wirkung entfalten [46, 47].…”