Solubility study of m-aminobenzoic acid form III in different mono-solvents by thermodynamic analysis and molecular simulation

Liu, Chunyan; Guo, Zhenxiao; Wang, Yuanyuan; Xiao, Yiting; Bao, Ying

doi:10.1016/j.molliq.2022.118871

Cited by 4 publications

(3 citation statements)

References 37 publications

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“…As an indispensable pharmaceutical intermediate, it is widely used in the synthesis of painkillers, antihypertensive drugs, vasodilators, etc. [5]. In addition, it has great applications in the synthesis of new organic luminescent materials, electrochemical materials, azo dyes, plant growth regulators, and so on [52,53].…”

Section: Biosynthesis Of Mabamentioning

confidence: 99%

“…The most stable form of these vitamins is fully oxidized pteroylglutamic acid (PteGlu). Due to the different oxidation states within the pterin ring, different 1C-units connected at positions N 5 and/or N 10 (typically 1C-units in the form of methyl (CH 3 -), formyl (HCO-), or methenyl (-CH + -) groups), and changes in the length of the glutamyl tail, a large number of different forms of folates are produced [46] (Figure 2). Many physiological processes, such as the biosynthesis of purine and thymidine monophosphate, the regeneration of methionine and the translation of mitochondrial protein, require folate for 1C-unit transfer [61].…”

Section: Folatementioning

confidence: 99%

“…PABA is a key intermediate in the biosynthesis of folate [4]. MABA is an essential pharmaceutical intermediate and it also finds significant applications in the synthesis of novel organic luminescent materials and plant growth regulators [5]. In addition, derivatives of ABA have been found to possess antibacterial and insecticidal properties.…”

Section: Introductionmentioning

confidence: 99%

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A New Direction for the Green, Environmentally Friendly and Sustainable Bioproduction of Aminobenzoic Acid and Its Derivatives

Xiao,

Zeng,

Wang

et al. 2024

Sustainability

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Aminobenzoic acid and its derivatives are a class of aromatic compounds that are important foundational chemicals for various dyes, food additives, and pharmaceuticals. Their production relies on chemical synthesis using petroleum-derived substances such as benzene as precursors, but due to the toxicity, environmental pollution, and non-renewable nature of raw materials in chemical synthesis, some suitable alternative methods are gradually being developed. Green, environmentally friendly, and sustainable biosynthesis methods have gradually been favored by researchers, especially after the discovery of the synthetic pathways of aminobenzoic acid and its derivatives in plants and microorganisms. Based on the purpose of protecting the ecological environment, reducing the use of non-renewable resources, and providing theoretical support for industrial green development, this article reviews the biosynthesis pathways of ortho-aminobenzoic acid, meta-aminobenzoic acid, para-aminobenzoic acid, and its derivatives such as catechol, folic acid, etc., and lists some examples of biosynthesis, analyzes their advantages and disadvantages, summarizes and looks forward to the future development direction of biosynthesis of aminobenzoic acid and its derivatives.

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Section: Biosynthesis Of Mabamentioning

confidence: 99%