Solubility measurement, correlation and mixing properties of thioacetamide in fifteen pure solvents

Huang, Longjie; Li, Xiaofang; Han, Runlin; Li, Yajun; Xu, Lingfeng; Zeng, Zhaoyun; Wu, Kui

doi:10.1016/j.molliq.2022.119847

Cited by 12 publications

(3 citation statements)

References 44 publications

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“…The modified Apelblat equation, λh equation and Wilson model are employed to analyze the correlation of the solubility data of resmetirom (form A) in pure solvents, and J–A–V model are utilized for correlation of solubility data of form A in propanol + heptane, as outlined in Table 4 . 33,34 The applicability as well as the accuracy of these four equations for determining the solubility of resmetirom are assessed using the average relative deviation (ARD%) as shown below: 35 where, x i exp and x i cal refer to the experimental and calculated solubility data of resmetirom (form A), respectively. N is the number of data.…”

Section: Resultsmentioning

confidence: 99%

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Solubility determination, dissolution properties and solid transformation of resmetirom (form A) in heptane and seven alcohols

Liu

Yuan

et al. 2023

RSC Adv.

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Section: Resultsmentioning

confidence: 99%

“…Drawing 4. 33,34 The applicability as well as the accuracy of these four equations for determining the solubility of resmetirom are assessed using the average relative deviation (ARD%) as shown below: 35…”

Section: Model Evaluationmentioning

confidence: 99%

Solubility determination, dissolution properties and solid transformation of resmetirom (form A) in heptane and seven alcohols

Liu

Yuan

et al. 2023

RSC Adv.

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“…The KAT-LSER model is used to study the effect of solvent on dissolution behavior, − and the formula is as follows: ln nobreak0em.25em⁡ x = C 0 + C 1 π * prefix+ C 2 β + C 3 α + C 4 ( V s δ H 2 100 R T ) α is the hydrogen bond acidity of the solvent. β is the hydrogen bond basicity of the solvent.…”

Section: Results and Discussionmentioning

confidence: 99%

Solubility Determination and Analysis of Phenol Red in Monosolvent and Binary Mixed Solvent at T = 278.15–323.15 K

Cheng,

Zhang,

Yang

et al. 2023

J. Chem. Eng. Data

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The solubility and thermodynamic characteristics of phenol red were determined by the static equilibrium method combined with HPLC. The equilibrium solubility of phenol red in 12 monosolvents (methanol, ethanol, npropanol, isopropanol, n-butanol, isobutanol, acetonitrile, methyl acetate, ethyl acetate, DMF, water, and acetone) was measured at a temperature range of 278.15−323.15 K and a constant pressure of 101.1 kPa. The results showed that in the experimental temperature range, the solubility of phenol red is positively correlated with the temperature and reached the maximum and minimum values in DMF and isobutanol. Ethanol, acetonitrile, and water were randomly selected to form three groups of binary mixed solvents, the monosolvent with high solubility is used as the cosolvent in the binary mixed solvent, and the solubility data were measured under the same experimental conditions. Interestingly, in all binary mixed solvents, the solubility data of phenol red showed a trend of first increasing and then decreasing with the increase of the proportion of cosolvent. The Buchowski−Ksiazaczak λh model and Apelblat model were used to fit the solubility data of phenol red in monosolvent, and the average root mean square deviation (RMSD) values are 3.8775 × 10 −2 and 4.6592 × 10 −3 . The Jouyban−Acree model, CNIBS/R-K model, and Sun model were used to fit the solubility data of phenol red in binary mixed solvent, and the average RMSD values were 9.4265 × 10 −6 , 5.1215 × 10 −6 , and 9.4265 × 10 −6 . Furthermore, the solvation of phenol red was investigated by the KAT-LSER model. The results showed that the acidity of the hydrogen bond had a significant effect on the solubility, and the contribution rate was 35.5%.

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Solvents and Solutes: Interaction, Dissolution, Power

2024

Handbook of Solvents, Volume 1

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Solubility measurement, correlation and mixing properties of thioacetamide in fifteen pure solvents

Cited by 12 publications

References 44 publications

Solubility determination, dissolution properties and solid transformation of resmetirom (form A) in heptane and seven alcohols

Solubility determination, dissolution properties and solid transformation of resmetirom (form A) in heptane and seven alcohols

Solubility Determination and Analysis of Phenol Red in Monosolvent and Binary Mixed Solvent at T = 278.15–323.15 K

Solvents and Solutes: Interaction, Dissolution, Power

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