Solubility diagram of lactose and lactulose in water

Abstract

The solubiiity of lactose in water can be found in Landolt-Bornstein where values are given for a-and /?-lactose. In the making of the diagram the small differences in solubility of a-and /?-lactose were ignored, as was done with lactulose. In this way a three-component system resulted.Components: Lactose hydrate, technical pure; [a]: = + 51.3'. Lactulose: prepared as described in a previous article published in this 2. Solubility diagram of lactose and lactulose in water at 30": The hatched part indicates uncertainties in the solubility of pure lactulose in water.

Trends in lactose-derived bioactives: synthesis and purification

“…On the other hand, most of the physiochemical properties of lactose and lactulose are similar, so that their separation by the techniques mentioned in the previous sections is quite challenging. Nevertheless, their solubilities are much different in water [150] and even more so in the presence of ethanol [151]. Thus, selective precipitation of lactose with ethanol appears as a sound technique for lactulose purification.…”