Solophenols B–D and Solomonin: New Prenylated Polyphenols Isolated from Propolis Collected from The Solomon Islands and Their Antibacterial Activity.

Inui, Saori; Hosoya, Tsuyoshi; Shimamura, Yuko; Masuda, S.; Ogawa, Takeshi; Kobayashi, Hirokazu; Shirafuji, Kenichi; Moli, Reuben T.; Kozone, Ikuko; Shin‐ya, Kazuo; Kumazawa, Shigenori

doi:10.1021/jf303516w

Cited by 38 publications

(26 citation statements)

References 22 publications

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“…Thus, this type of propolis from the Pacific region are called 'Pacific propolis' [1]. Further we isolated some prenylflavonoids from the Solomon Islands and Hawaii identical to those found from Okinawan propolis [9,10]. These findings indicate that the propolis from the Solomon Islands and Hawaii have the same botanical origin, M. Tanarius, as Okinawan propolis.…”

Section: -2supporting

confidence: 57%

Bioactive compounds in bee propolis for drug discovery

Kumazawa

2018

AIP Conference Proceedings

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Section: -2supporting

confidence: 57%

Bioactive compounds in bee propolis for drug discovery

Kumazawa

2018

AIP Conference Proceedings

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“…Prenylated flavanone-type compounds, which were previously classified as a chemical marker of Pacific HBP, have been found not only in Asia (Japan [ 75 , 85 ], Oman [ 125 ], and Taiwan [ 70 , 84 ]), and Oceania (Fiji [ 143 ] and Solomon Island [ 106 , 117 , 118 ]), but also in Africa (Egypt [ 92 , 100 ] and Nigeria [ 141 ]). These compounds originated from Macaranga spp.…”

Section: Propolis Components: Chemistry and Geographical Distributmentioning

confidence: 99%

Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components

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Ogbourne

Brooks

et al. 2020

IJMS

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Propolis is a natural resinous material produced by bees and has been used in folk medicines since ancient times. Due to it possessing a broad spectrum of biological activities, it has gained significant scientific and commercial interest over the last two decades. As a result of searching 122 publications reported up to the end of 2019, we assembled a unique compound database consisting of 578 components isolated from both honey bee propolis and stingless bee propolis, and analyzed the chemical space and chemical diversity of these compounds. The results demonstrated that both honey bee propolis and stingless bee propolis are valuable sources for pharmaceutical and nutraceutical development.

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“…In the past few years, prenylated quercetin analogs, such as solophenol D and uralenol, have gained a lot of attention due to their antibacterial properties. It has been reported that prenylation may enhance the biological functions of quercetin by increasing its hydrophobicity and bioavailability [ 23 , 24 ].…”

Section: Chemistry Of Quercetin and Its Analogsmentioning

confidence: 99%

Molecular Targets Underlying the Anticancer Effects of Quercetin: An Update

et al. 2016

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Quercetin, a medicinally important member of the flavonoid family, is one of the most prominent dietary antioxidants. It is present in a variety of foods—including fruits, vegetables, tea, wine, as well as other dietary supplements—and is responsible for various health benefits. Numerous pharmacological effects of quercetin include protection against diseases, such as osteoporosis, certain forms of malignant tumors, and pulmonary and cardiovascular disorders. Quercetin has the special ability of scavenging highly reactive species, such as hydrogen peroxide, superoxide anion, and hydroxyl radicals. These oxygen radicals are called reactive oxygen species, which can cause oxidative damage to cellular components, such as proteins, lipids, and deoxyribonucleic acid. Various oxygen radicals play important roles in pathophysiological and degenerative processes, such as aging. Subsequently, several studies have been performed to evaluate possible advantageous health effects of quercetin and to collect scientific evidence for these beneficial health claims. These studies also gather data in order to evaluate the exact mechanism(s) of action and toxicological effects of quercetin. The purpose of this review is to present and critically analyze molecular pathways underlying the anticancer effects of quercetin. Current limitations and future directions of research on this bioactive dietary polyphenol are also critically discussed.

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Solophenols B–D and Solomonin: New Prenylated Polyphenols Isolated from Propolis Collected from The Solomon Islands and Their Antibacterial Activity.

Cited by 38 publications

References 22 publications

Bioactive compounds in bee propolis for drug discovery

Bioactive compounds in bee propolis for drug discovery

Lessons from Exploring Chemical Space and Chemical Diversity of Propolis Components

Molecular Targets Underlying the Anticancer Effects of Quercetin: An Update

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