Solitary superficial acral angiomyxoma: An infrequently reported soft tissue tumor

Abstract

Superficial angiomyxomas (SA) are clinically variable, infrequent, benign skin lesions. They are usually located on the trunk, but can also appear on the lower limbs, head, and neck. The present case, hence, is unusual, because the lesion developed on the toe. They are diagnosed histologically, and are characterized by being poorly delimited tumors with the presence of interstitial myxoid material and scanty cellularity. We discuss the clinical and histological features of digital SA as well as a brief outline of other myxoid lesions.

Cyto-histo correlation of a very rare tumor: Superficial angiomyxoma

“…in the toe. [ 9 10 11 ] Our case also had no other swellings besides the one with which the patient presented with; moreover, the swelling was not accompanied by noncutaneous myxomas, pigmentation of the skin or mucous membrane, or endocrine disorders.…”

Sonographic findings in superficial angiomyxoma of the vulva in a perimenopausal female

“…[378] Almost all reported cases of vulvar SAM have been confined to the subcutaneous adipose layer and often exhibit nodular growth and papular skin disease. [4] In such cases, ultrasonography reveals an oval or circular heterogeneous hypoechoic mass that may be accompanied by posterior echo enhancement, a capsule, a clear boundary, and an abundant blood flow signal in the mass.…”

“…SAM can occur in the labia of the vulva, but such cases are easily misdiagnosed as vestibular large gland cysts because of rich lymphatic characteristic. [4] Some scholars have argued that the abundant vessels and the extremely loose myxomatous stroma observed beneath the epidermis in affected patients might promote the spread of infection. [9] Circulatory nodular fasciitis mainly occurs in the deep layer of the fascia and subcutaneous fat and often lacks capsules.…”

“…[2] It can occur in many parts of the body but mainly presents in the head, neck, limbs, and trunk. [34] While SAM occurs at all ages, it primarily develops in middle-aged individuals (20–40 years) and is slightly more common in males than in females. [5] Most publications on this disease are case reports.…”

Superficial acral fibromyxoma

“…It is locally recurrent, nonmetastatic but occurs more commonly in the fourth decade, and histologically, there is prominent vascularization with myxoid stroma and mucin pools with inflammatory cell component. [ 8 ] Digital myxoid cyst arises on or around the distal interphalangeal joint and shows a well-circumscribed, deposit of mucin but few fibroblasts without more vascularity. Cutaneous focal mucinosis lacks a lobular architecture and is acellular with few blood vessels.…”