Solitary preperitoneal neurofibroma: a case report

Njoumi, Noureddine; Elabsi, M.; Attolou, Gilles; Elouazzani, H.; Elalami, Faricha Hassan; Chkoff, M. R.

doi:10.1186/s13104-015-1098-8

Cited by 12 publications

(12 citation statements)

References 16 publications

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“… 19 They are unpredictable and need long-term follow-up after surgical tumor removal. 20 However, in the current case, two separate but adjacent nerve sheath tumors originated from the ulnar nerve. One of the predisposing factors for such a condition is neurofibromatosis, which can produce a wide range of PNSTs highlighting the need for careful preoperative examination.…”

Section: Discussionmentioning

confidence: 52%

Schwannoma and Neurofibroma, Originating from the Ulnar Nerve in Neurofibromatosis: A Case Report and Review of the Literature

et al. 2020

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Schwannomas and neurofibromas are rare benign tumors originating from the peripheral nerve sheath. Tumors in neurofibromatosis are mostly neurofibromas and often appear in the soft tissue of peripheral nerves. In this report, a patient presented with two large adjacent soft tissue tumors in the right wrist and distal forearm which originated from a common nerve. A schwannoma had formed beside a neurofibroma from the ulnar nerve and induced numbness and paresthesia in the little and ring fingers. Although the patient had café au lait spots on the skin, neurofibromatosis was not suspected due to lack of symptoms. The patient was referred to the current research clinic suffering from two soft tissue masses in the wrist and ulnar nerve dysfunction. In neurofibromatosis patients, two tumors of a different nature originating from a common nerve close together have rarely been described in the literature. The patient was treated by en bloc excision of the mass while protecting the nerve fascicles. The follow-up results indicated no neurological symptoms and complete restoration of ulnar nerve function.

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Section: Discussionmentioning

confidence: 52%

Schwannoma and Neurofibroma, Originating from the Ulnar Nerve in Neurofibromatosis: A Case Report and Review of the Literature

et al. 2020

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“…Neurofibroma is a benign lesion that originates on the peripheral nerve sheath, the same as MPNST [11]. The most common sites of neurofibromas are cutaneous nerves of the body, neck, and head.…”

Section: Discussionmentioning

confidence: 99%

“…The most common sites of neurofibromas are cutaneous nerves of the body, neck, and head. A single lesion of neurofibroma has no specific symptoms [11]. The treatment of choice is excision; the prognosis of neurofibroma is better than that of MPNST, and postoperative malignant changes or local recurrences are very rare [11].…”

Section: Discussionmentioning

confidence: 99%

Superficial malignant peripheral nerve sheath tumor from recurrent neurofibroma in the abdominal wall of a patient without neurofibromatosis type 1

Jung¹,

Bae²,

Choi³

et al. 2019

Yeungnam Univ J Med

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Malignant peripheral nerve sheath tumor (MPNST) is rare, accounting for 5–10% of all soft tissue sarcomas. MPNST is characteristically aggressive and has a poor prognosis. Fifty percent of patients with MPNST have neurofibromatosis type 1 (NF1). NF-associated MPNST occurs more often at younger ages than sporadic MPNST, but the survival difference is controversial. Superficial MPNST from a recurrent neurofibroma is extremely rare and only a limited number of cases have been reported in the literature. Herein, we report an unusual case of superficial MPNST from a recurrent neurofibroma in a patient without NF1.

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“…Ten to 23% of fibrous solitary tumors of the soft tissue can be malignant (8). These tumors are unpredictable and long-term followup after surgery and removing the tumor should be done (9).…”

Section: Discussionmentioning

confidence: 99%

Solitary Neaurofibroma in Lower Extremity with Central Extensive Hyalinization

et al. 2017

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Introduction: Neurofibroma is a rare benign tumor that often originates from peripheral nerve sheath. The solitary type can be seen in middle-aged people. Hyalinization is a rare phenomenon that can be observed in fibrous tumors. Case Presentation: In this report, a 46-year-old male patient with a hard mass in proximal femoral is presented. He had central necrosis in the initial imaging studies. The mass was painful and caused signs of local anesthetic for the patient. Extensive hyalinization was observed in the central part of the mass in histopathological studies. S100 protein was widely positive, but CD34 and bcl2 were negative. No necrosis was observed. Conclusions:The extensive central hyalinization is very rare in fibrous tumors and is observed for the first time in neurofibroma. Hyalizination in the work up prior to surgical treatment led to misdiagnosis of the radiologist and the surgeon. Detailed pathological examination is very important to definitive diagnosis.

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Solitary preperitoneal neurofibroma: a case report

Cited by 12 publications

References 16 publications

Schwannoma and Neurofibroma, Originating from the Ulnar Nerve in Neurofibromatosis: A Case Report and Review of the Literature

Schwannoma and Neurofibroma, Originating from the Ulnar Nerve in Neurofibromatosis: A Case Report and Review of the Literature

Superficial malignant peripheral nerve sheath tumor from recurrent neurofibroma in the abdominal wall of a patient without neurofibromatosis type 1

Solitary Neaurofibroma in Lower Extremity with Central Extensive Hyalinization

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