Solitary Plasmacytoma of the Calvarium: Two Cases Treated by Operation Alone

Arienta, Cesare; Caroli, Manuela; Ceretti, L.; Villani, R.

doi:10.1227/00006123-198710000-00022

Cited by 34 publications

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“…Our patient underwent surgery with complete resection of tumor (Figure 2). Nevertheless, Arienta et al reported that if total resection has been achieved then radiotherapy should be reserved for case of tumor recurrence [1]. Furthermore, there are reports of complete cure after radiotherapy, because plasma cell neoplasms are exquisitely radiosensitive [14].…”

Section: Discussionmentioning

confidence: 99%

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Solitary Plasmocytoma of the Vault

Baallal¹

2014

Med chem

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Solitary plasmocytoma is rarely located in the cranial vault. We report a case of a 46-year-old Moroccan man who consulted for a medial and paramedian frontal swelling. Clinical examination revealed a large soft mass in the region frontal. Computed tomography and magnetic resonance imaging revealed an extra-axial mass. The lesion was totally excised despite the bleeding tendency. Histology disclosed the presence of a plasmacytoma. On follow up examination 3 years later no tumor recurrence or multiple myeloma was detected.

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Section: Discussionmentioning

confidence: 99%

“…Craniocerebral localization is rare and constitutes only 0.7 per 100 of all solitary plasmacytomas. They fall into two groups [1]. Those arising from the cranial bones (plasmacytoma of the skull, osseous form) and those arising from the dura mater (dural plasmacytoma, non-osseous form).…”

Section: Introductionmentioning

confidence: 99%

Solitary Plasmocytoma of the Vault

Baallal¹

2014

Med chem

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“…1,8) However, intracranial plasmacytoma is very radiosensitive so complete surgical resection and adjuvant radiation therapy is sometimes curative. 2,12,14,25) Therefore, the radiotherapy is given in most cases.…”

Section: Discussionmentioning

confidence: 99%

“…Recent reports suggest that definitive treatment should consist of complete surgical resection with adjuvant radiation therapy. 1,16) Based on this suggestion, our Case 2 received postoperative radiotherapy after total resection of the tumor.…”

Section: Discussionmentioning

confidence: 99%

Solitary Plasmacytoma of the Skull: Immunohistochemical Study of Angiogenic Factors and Syndecan-1-Two Case Reports-

Naganuma

Sakatsume

Sugita

et al. 2004

Neurol. Med. Chir.(Tokyo)

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Two cases of solitary plasmacytomas of the skull are presented, and some biological aspects of the tumor examined. A 75-year-old woman presented with a tumor in the right parietal region. The serum level of immunoglobulin G (IgG) was high and a urine test for Bence Jones protein was negative. A reddish vascular mass was totally removed at surgery. The serum level of IgG was within normal limits after the operation. Postoperative radiotherapy was not performed. A 58-year-old woman presented with a tumor in the occipital region. Serum levels of Igs were within normal limits. A urine test for Bence Jones protein was positive for Ig kappa chain. Bone marrow aspiration revealed no evidence of systemic myelomatosis. The tumor mass was totally removed at surgery and she received local radiation therapy (total 50 Gy). Three months after the surgery, Bence Jones protein (kappa chain) was detected in both the urine and serum and bone scintigraphy showed a weak hot spot in the iliac bone, suggesting development to multiple myeloma. Immunohistochemical studies showed that most tumor cells were positive for vascular endothelial growth factor and syndecan-1, and some tumor cells were strongly positive for basic fibroblast growth factor in both cases. The Ki-67 staining indices were 11.3% and 15.6%. Tumor tissues were negative for p53. These results suggest that solitary plasmacytoma of the skull expresses the angiogenic factors, vascular endothelial growth factor, and basic fibroblast growth factor, in accordance with the high vascularity of the tumors, and syndecan-1 may be an immunohistochemical marker of solitary plasmacytoma of the skull.

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“…Solitary plasmacytoma is a circumscribed neoplastic lesion with no clinical or radiological signs of systemic involvement and accounts for some 7 % of myelomas [1,6,8,21]. Solitary bone plasmacytoma is described as a single lytic lesion without signs of myeloma cells on bone marrow examination, even when paraproteins are present in serum and/or urine.…”

Section: Introductionmentioning

confidence: 99%

Solitary plasmacytoma of the calvarium: a review of clinical and prognostic features

Cervoni

Salvati

1998

Neurosurg. Rev.

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Primary craniocerebral plasmacytomas are uncommon they represent only 0.7% of all plasmacytomas. We report one case of solitary plasmacytoma of the skull and discuss the clinical features and prognosis of this tumor. There seems to be no difference in prognosis between plasmacytomas originating from the bone (osseous form) and those originating from the dura mater (non-osseous form). In these lesions, the risk of secondary multiple myeloma appears to be low.

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Solitary Plasmacytoma of the Calvarium: Two Cases Treated by Operation Alone

Cited by 34 publications

References 0 publications

Solitary Plasmocytoma of the Vault

Solitary Plasmocytoma of the Vault

Solitary Plasmacytoma of the Skull: Immunohistochemical Study of Angiogenic Factors and Syndecan-1-Two Case Reports-

Solitary plasmacytoma of the calvarium: a review of clinical and prognostic features

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