Solitary plaque on the leg of a child: A report of two cases and a brief review of acral pseudolymphomatous angiokeratoma of children and unilesional mycosis fungoides

Evans, Megan S.; Burkhart, Craig N.; Bowers, Edith V.; Culpepper, Keliegh S.; Magro, Cynthia M.

doi:10.1111/pde.13686

Cited by 6 publications

(8 citation statements)

References 16 publications

(38 reference statements)

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“…Although rare, several case reports have emerged describing unilesional MF in children. Unilesional MF is typically characterized by a single erythematous patch or plaque with overlying scale . The lesion typically arises on non–sun‐exposed skin and is often present for several years prior to diagnosis …”

Section: Clinical Presentationmentioning

confidence: 99%

“…Unilesional MF is typically characterized by a single erythematous patch or plaque with overlying scale. 29 The lesion typically arises on non-sun-exposed skin and is often present for several years prior to diagnosis. 29,30…”

Section: Prognosismentioning

confidence: 99%

“…29 The lesion typically arises on non-sun-exposed skin and is often present for several years prior to diagnosis. 29,30…”

Section: Prognosismentioning

confidence: 99%

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Mycosis fungoides in pediatric patients: Clinical features, diagnostic challenges, and advances in therapeutic management

Cohen

Sweren

2019

Pediatric Dermatology

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Mycosis fungoides (MF) is the most common primary cutaneous lymphoma in pediatric patients. Given the indolent nature of MF, symptoms often present in childhood but may not be diagnosed as MF until adulthood. Delayed diagnosis is associated with poor long‐term prognosis. Thus, increased clinician recognition and accurate diagnosis of early‐stage MF in pediatric patients is critically important. In this review, we summarize the clinical features of the most common pediatric MF subtypes and highlight important differences between pediatric and adult MF. Moreover, we reviewed all pediatric MF case series published between 2008 and 2018 to analyze treatment modalities and identify emerging therapies. As treatment of pediatric MF is complex, selection of therapy varies significantly depending upon the specific clinical characteristics, disease severity, and patients' preferences.

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Section: Clinical Presentationmentioning

confidence: 99%

Section: Prognosismentioning

confidence: 99%

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Mycosis fungoides in pediatric patients: Clinical features, diagnostic challenges, and advances in therapeutic management

Cohen

Sweren

2019

Pediatric Dermatology

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“…To the best of our knowledge, the presence or absence of CD30 in APACHE has not been studied immunohistochemically. A PCR analysis reveals that APACHE is a polyclonal disorder [25,26].…”

Section: Acral Pseudo-lymphomatous Angiokeratoma Of Childrenmentioning

confidence: 99%

Pseudomalignancies in Children: Histological Clues, and Pitfalls to Be Avoided

Menzinger

Fraïtag

2021

Dermatopathology

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The term “pseudomalignancy” covers a large, heterogenous group of diseases characterized by a benign cellular proliferation, hyperplasia, or infiltrate that resembles a true malignancy clinically or histologically. Here, we (i) provide a non-exhaustive review of several inflammatory skin diseases and benign skin proliferations that can mimic a malignant neoplasm in children, (ii) give pathologists some helpful clues to guide their diagnosis, and (iii) highlight pitfalls to be avoided. The observation of clinical–pathological correlations is often important in this situation and can sometimes be the only means (along with careful monitoring of the disease’s clinical course) of reaching a firm diagnosis.

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“…The annual incidence varies between 0.3 and 0.96 cases per 100,000 persons [9], typically affecting patients between 45 and 65 years of age, with a male to female sex ratio of 2:1. Childhood and adolescent MF cases are more exceptional [10][11][12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

A Comprehensive Update of the Atypical, Rare and Mimicking Presentations of Mycosis Fungoides

Lebas

Collins

Somja

et al. 2021

Dermatol Ther (Heidelb)

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Solitary plaque on the leg of a child: A report of two cases and a brief review of acral pseudolymphomatous angiokeratoma of children and unilesional mycosis fungoides

Cited by 6 publications

References 16 publications

Mycosis fungoides in pediatric patients: Clinical features, diagnostic challenges, and advances in therapeutic management

Mycosis fungoides in pediatric patients: Clinical features, diagnostic challenges, and advances in therapeutic management

Pseudomalignancies in Children: Histological Clues, and Pitfalls to Be Avoided

A Comprehensive Update of the Atypical, Rare and Mimicking Presentations of Mycosis Fungoides

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