Solitary ovarian plasmacytoma. A case report and review of literature

Feldman, Aharon; Isrow, Derek; Schultz, Daniel; Inamdar, Kedar; Rasool, Nabila; Elshaikh, Mohamed A.

doi:10.1016/j.gore.2015.05.001

Cited by 4 publications

(4 citation statements)

References 14 publications

(24 reference statements)

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“…Extramedullary plasmacytoma is rare, accounting for 1% of all plasma cell neoplasm. They occur most commonly in the upper aerodigestive tract, but other localizations are possible such as lymph nodes, bladder, breasts, thyroid, testes, parotid glands, skin, and central nervous system [ 2 ]. The ovarian localization remains exceptional.…”

Section: Discussionmentioning

confidence: 99%

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Ovarian plasmacytoma: a case report

Haloui¹,

Karich²,

Akouh³

et al. 2023

Pan Afr Med J

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Plasmacytomas are a rare spectrum of plasma cell neoplasms that are single localized tumours, lacking the clinical features of plasma cell myeloma with no radiographical evidence of additional plasma cell tumours. Two clinical variants of plasmacytomas can be distinguished: solitary plasmacytoma of bone and extramedullary (or extraosseous) plasmacytoma. The latter is rare, representing 1% of all plasma cell neoplasms, occurring most frequently in the upper airways. Ovarian localization is exceptional, with only a few cases being reported in the literature. We herein report a case of an ovarian extramedullary plasmacytoma occurring in a 56-year-old woman who consulted for abdominal pain and abdominal mass, while highlighting the main histological and immunohistochemical features of this rare malignancy, along with a thorough review of literature gathering all cases of ovarian plasmacytomas reported to date.

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Section: Discussionmentioning

confidence: 99%

“…Only a few cases of ovarian plasmacytomas have been reported in literature, all of them being reported as single cases. In our review of the bibliography, we have listed 18 cases, including our present case ( Table 1 ) [ 2 - 20 ].…”

Section: Discussionmentioning

confidence: 99%

Ovarian plasmacytoma: a case report

Haloui¹,

Karich²,

Akouh³

et al. 2023

Pan Afr Med J

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“…These include beta 2-immunoglobulin, blood counts, electrolytes, serum-free light chains, and serum protein electrophoresis. [2,12] Unlike MM, EMP usually does not exhibit serum M protein or Bence Jones light chains in urine. Nevertheless, EMP may show M protein in up to 25% of cases.…”

Section: Discussionmentioning

confidence: 99%

“…In 5%-10% of reported solitary plasmacytomas, the lesions may be found outside the bone marrow and are named solitary EMPs. [2] Voigt reported the first case of EMP in 1938, [3] but half of the reported cases have been published in the past 8 years [Table 1], [2][3][4][5][6][7][8][9][10][11][12][13][14] potentially indicating greater detection or incidence. EMP is a rare primary soft-tissue plasma cell tumor commonly found in the head and neck, with 90% occurring in the upper aerodigestive tract.…”

Section: Introductionmentioning

confidence: 99%

Plasmacytoma of the ovary

Elamouri

Shaffouh

Torjman

2021

Ibnosina Journal of Medicine and Biomedical Sciences

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Extramedullary plasmacytoma is a rare plasma cell neoplasm that involves the ovary very rarely. Here, I report a case of primary ovarian plasmacytoma in a 42-year-old patient. The patient presented with abdominal distention, and workup showed a left ovarian mass (6.5 cm × 8 cm) with marked ascites. The patient had a hysterectomy with bilateral salpingo-oophorectomy. Histopathologic, immunohistochemical, bone marrow examination, and other relevant examinations established the diagnosis of primary ovarian plasmacytoma with kappa light chain restriction. No evidence of malignancy in the omentum and ascitic fluid was detected. The patient did not need postoperative chemotherapy or radiotherapy, and 6-month follow-up was uneventful. Due to the scarcity of information on these extremely rare tumors with abdominal masses, the diagnosis should be considered if complete surgical resection is achieved and no evidence of multiple myeloma is found.

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Management of gynaecologic plasmacytoma: A review article

Feldman

Zhang

Buekers

et al. 2016

Journal of Obstetrics and Gynaecology

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In contrast to multiple myeloma (MM) which exhibits diffuse bone marrow and other organ involvement, solitary plasmacytomas carry a favourable prognosis. Extramedullary plasmacytomas (EMP) are a unique form of plasma cell neoplasms. These tumours are rare in the female reproductive tract. Only 24 cases of gynaecologic plasmacytomas were reported to date (7 cases were solitary plasmacytomas and 17 cases were either part of disseminated MM with involvement of a gynaecologic organ or were lacking complete work-up to rule out MM). The standard care of gynaecologic solitary EMP is surgical resection alone when feasible. Adjuvant radiation therapy may be considered for adverse prognostic factors such as positive resection margins. MM with gynaecologic organ involvement should be managed with systemic therapy and defer local therapies to symptomatic progression.

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Solitary ovarian plasmacytoma. A case report and review of literature

Abstract: HighlightsA patient with rare solitary ovarian plasmacytoma is reportedDiagnostic work-up is mandatory to rule out ovarian involvement as part of multiple myeloma.After complete surgical resection, the prognosis appears to be very favorable.

Cited by 4 publications

References 14 publications

Ovarian plasmacytoma: a case report

Ovarian plasmacytoma: a case report

Plasmacytoma of the ovary

Management of gynaecologic plasmacytoma: A review article

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