Solitary Myofibroma of the Sclera

Choopong, Pitipol; Nielsen, Petur; Perlman, Elliot M.; Huang, John J.; Dryja, Thaddeus P.; Foster, C. Stephen

doi:10.1097/01.ico.0000243951.07096.fd

Cited by 5 publications

(2 citation statements)

References 20 publications

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“…In the literature, 1 case of solitary scleral myofibroma 3 and 1 case of solitary conjunctival myofibroma 28 have been described so far.…”

Section: Discussionmentioning

confidence: 99%

“… 2 The tumorous lesions are most commonly located in the head and neck region and can present on the skin, soft tissue, bone, and visceral organs. Rare cases of ocular and periocular tissue involvement have been described including lesions of the sclera, 3 as well as extraocular lesions of the eyelid skin, periorbital soft tissue, and orbital bones. 4 Skin lesions are typically diagnosed early in life as they present as painless, subcutaneous, nodular, and blueish skin alterations with slight skin discoloration due to vascularization.…”

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confidence: 99%

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Corneal Infantile Myofibromatosis Caused by Novel Activating Imatinib-Responsive Variants in PDGFRB

Howaldt,

Lenglez,

Velmans

et al. 2024

Ophthalmology Science

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“…In the literature, 1 case of solitary scleral myofibroma 3 and 1 case of solitary conjunctival myofibroma 28 have been described so far.…”

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Corneal Infantile Myofibromatosis Caused by Novel Activating Imatinib-Responsive Variants in PDGFRB

Howaldt,

Lenglez,

Velmans

et al. 2024

Ophthalmology Science

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Connective tissue tumors

Calonje¹,

Brenn²,

Lazar³

2012

McKee's Pathology of the Skin

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Solitary adult orbital myofibroma: Report of a case and review of the literature

Morrow

Tanas

Syed

et al. 2020

American Journal of Ophthalmology Case Reports

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Purpose Myofibromas are benign soft tissue tumors commonly encountered in infancy and childhood. Developing usually within the first two years of life, they can be multicentric and involve deep visceral organs. Observations We present the rare occurrence of a solitary orbital myofibroma in an adult patient. The clinical, histopathologic and immunohistochemical findings of the tumor are documented. Conclusions A comprehensive review of pediatric and adult orbital and periocular involvement by myofibroma is presented. Its characteristic pathologic and molecular findings are reviewed. Importance Myofibromas are uncommon but important tumors that can occur in the head and neck region, including the orbit. Seen more often in children, they can rarely be encountered in adult patients. Diagnosis is possible with a panel of immunostains and molecular analysis can be further confirmatory.

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Solitary Myofibroma of the Sclera

Abstract: Myofibroma should be considered in the differential diagnosis of an epibulbar mass, especially in the setting that would mimic nodular scleritis.

Cited by 5 publications

References 20 publications

Corneal Infantile Myofibromatosis Caused by Novel Activating Imatinib-Responsive Variants in PDGFRB

Corneal Infantile Myofibromatosis Caused by Novel Activating Imatinib-Responsive Variants in PDGFRB

Connective tissue tumors

Solitary adult orbital myofibroma: Report of a case and review of the literature

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