Solitary Metastasis From Occult Follicular Carcinoma of the Thyroid Mimicking Trigeminal Neurinoma. Case Report.

Kachhara, Rajneesh; Nair, Suresh; Radhakrishnan, V. V.; Pandey, Manoj; Ahmed, Mohammed Iqbal; Kumar, Aswin; Bhattacharya, R. N.

doi:10.2176/nmc.41.360

Cited by 13 publications

(10 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The lung is the most common metastatic site of thyroid carcinoma, followed by the bone [11, 21, 45, 47]. Skull metastasis of thyroid carcinoma is rare, with a small number of reported cases [2–4, 6–8, 12, 19–24, 26–28, 30, 32–35, 38–40, 42, 44, 45, 49–51, 53, 54, 56, 57, 60, 63–65, 68–70, 73, 77, 78]. The largest series of skull metastasis from thyroid carcinoma reported a frequency of only 2.5% among 473 patients [45].…”

Section: Introductionmentioning

confidence: 99%

“…The largest series of skull metastasis from thyroid carcinoma reported a frequency of only 2.5% among 473 patients [45]. Moreover, skull base metastasis from DTC is even rarer, with only 28 reported cases, including 18 cases of skull base metastasis from FTC [6, 7, 24, 30, 39, 44, 45, 49, 50, 54, 56, 57, 60, 63, 69, 70, 78] and 10 cases from PTC [4, 12, 20, 23, 34, 38, 64, 65, 77] (Table 2). In this review article, the clinicopathological and molecular histochemical features and treatment modalities of skull base metastasis of DTC, namely, FTC and PTC, are discussed with a review of literatures on molecular pathogenesis.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Clinicopathological and Molecular Histochemical Review of Skull Base Metastasis from Differentiated Thyroid Carcinoma

Matsuno

Murakami

Hoya

et al. 2013

Acta Histochem. Cytochem

View full text Add to dashboard Cite

Skull base metastasis from differentiated thyroid carcinoma including follicular thyroid carcinoma (FTC) and papillary thyroid carcinoma (PTC) is a rare clinical entity. Eighteen FTC cases and 10 PTC cases showing skull base metastasis have been reported. The most common symptom of skull base metastasis from FTC and PTC is cranial nerve dysfunction. Bone destruction and local invasion to the surrounding soft tissues are common on radiological imaging. Skull base metastases can be the initial clinical presentation of FTC and PTC in the presence of silent primary sites. The possibility of skull base metastasis from FTC and PTC should be considered in patients with the clinical symptoms of cranial nerve dysfunction and radiological findings of bone destruction. A variety of genetic alterations in thyroid tumors have been identified to have a fundamental role in their tumorigenesis. Molecular histochemical studies are useful for elucidating the histopathological features of thyroid carcinoma. Recent molecular findings may provide novel molecular-based treatment strategies for thyroid carcinoma.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Clinicopathological and Molecular Histochemical Review of Skull Base Metastasis from Differentiated Thyroid Carcinoma

Matsuno

Murakami

Hoya

et al. 2013

Acta Histochem. Cytochem

View full text Add to dashboard Cite

show abstract

“…6,25) Only 25 adult cases of cerebral RTs, including AT/RTs and malignant RTs, have been reported. 1,2,8,10,[13][14][15]19,23,24,27,31,32,38,39,41,42,45) Only 6 cases of epithelioid glioblastoma with a rhabdoid component have been reported. 16,26,28,47) However, the World Health Organization (WHO) Classification of Tumours of the Central Nervous System classifies AT/RTs as embryonal tumors, but does not list malignant RT and rhabdoid glioblastoma as distinct categories.…”

Section: Introductionmentioning

confidence: 99%

Malignant Brain Tumor With Rhabdoid Features in an Adult -Case Report-

Mutou

Hirose

Ikeda

et al. 2011

Neurol. Med. Chir.(Tokyo)

View full text Add to dashboard Cite

Rhabdoid tumor (RT) of the central nervous system is an uncommon and aggressive neoplasm that usually affects pediatric patients. Currently, these tumors are classified as malignant RT or atypical teratoid/RT. Another entity of intraparenchymal brain tumor with a rhabdoid component is the extremely rare rhabdoid glioblastoma. A 23-year-old woman presented with a malignant RT in the right thalamus. The tumor was adjacent to the right lateral ventricle and was partially resected. Histological examination revealed prominent proliferation of rhabdoid cells, which is consistent with a diagnosis of malignant RT; the typical features of glioblastoma were not observed. The tumor cells stained positively for integrase interactor-1 and glial fibrillary acidic protein. Therefore, the tumor may have originated from glial components. Genetic analysis using comparative genomic hybridization showed a deoxyribonucleic acid copy-number gain on chromosome 7 but not on chromosome 22. The tumor did not respond to chemotherapy or radiotherapy, and the patient survived for only 4 months after surgery. The present case of malignant RTs shows certain similarities with those of rhabdoid glioblastoma. Further accumulation and analysis of data, including data from genetic analyses, may lead to the identification of a new type of malignant RT.

show abstract

“…The occurrence of metastases in Meckel's cave is described for esophageal and colorectal adenocarcinoma as well as breast carcinoma [5,6,12]. Intracranial metastases of the ophthalmic (V1), maxillary (V2) and mandibular (V3) nerves or the trigeminal nerve trunk have been reported previously with follicular carcinoma of the thyroid [13], systemic lymphoma [14], hepatocellular carcinoma, ovarian cancer and melanoma of the skin [15][16][17].…”

Section: Discussionmentioning

confidence: 99%

Metastases in Meckel's Cave

et al. 2007

View full text Add to dashboard Cite

Metastases in Meckel's cave are a rare tumor entity and should be considered as important differential diagnosis, especially if the patient presents with trigeminal neuralgia and suffers from a known primary malignancy. We present three cases of patients with secondary trigeminal neuralgia caused by a metastasis in Meckel's cave, treated by microsurgery and fractionated radiation therapy. Differential diagnoses are discussed on the basis of preoperative neuroradiological imaging. MRI is the preferred diagnostic modality, whereas complementary CT may be needed for evaluation of early bone invasion. ZusammenfassungDas Cavum Meckeli ist ein seltener Manifestationsort tumoraler Metastasen. Bei Patienten mit bekannter maligner Tumorerkrankung, die unter einer Trigeminusneuralgie leiden, sollte jedoch die Metastasierung des Cavum Meckeli in differentialdiagnostische Betrachtungen einbezogen werden. Wir präsentieren drei Fälle mit sekundärer Trigeminusneuralgie infolge Metastasierung des Cavum Meckeli. Alle drei Patienten wurden mittels Mikroneurochirurgie und fraktionierter Radiotherapie behandelt. Die Magnetresonanztomographie ist die Methode der Wahl in der Evaluation neuroradiologischer Differentialdiagnosen. Die Computertomographie ist sehr hilfreich zur Beurteilung knöcherner Arrosionen.

show abstract

Solitary Metastasis From Occult Follicular Carcinoma of the Thyroid Mimicking Trigeminal Neurinoma. Case Report.

Cited by 13 publications

References 13 publications

Clinicopathological and Molecular Histochemical Review of Skull Base Metastasis from Differentiated Thyroid Carcinoma

Clinicopathological and Molecular Histochemical Review of Skull Base Metastasis from Differentiated Thyroid Carcinoma

Malignant Brain Tumor With Rhabdoid Features in an Adult -Case Report-

Metastases in Meckel's Cave

Contact Info

Product

Resources

About