Solitary Mastocytoma

Holmberg, Lars

doi:10.1111/j.1651-2227.1970.tb16808.x

Search citation statements

Order By: Relevance

Paper Sections

Select...

Discussion1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1974

2007

Publication Types

Select...

Article4

Book1

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 6 publications

(1 citation statement)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Mastocytomas usually arise on the trunk and extremities; the palm and sole are considered to be unusual sites 1–3 . Review of literature revealed two case reports with involvement of the sole 4,5 and one with involvement of the palm 6 …”

Section: Discussionmentioning

confidence: 99%

A blistering plaque on the palm of an infant

et al. 2007

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

A blistering plaque on the palm of an infant

et al. 2007

View full text Add to dashboard Cite

Solitary mastocytoma of the eyelid

Scheck

Horny

Ruck

et al. 1987

Vichows Archiv A Pathol Anat

View full text Add to dashboard Cite

Solitary mastocytoma (mast cell naevus) of the skin represents a relatively rare dermal tumour. Its occurrence on the lower eyelid is exceptional. We report the case of a 4 month old male infant who exhibited a firm, yellowish nodule (1 cm in maximum diameter) on the lower lid of the right eye from birth. Histologically, the tumour consisted of strongly metachromatic tissue mast cells (TMC) infiltrating the whole dermis, the adjacent subcutaneous tissue and the lid muscle. Since comparable skin lesions in other sites were not observed, a diagnosis of solitary mastocytoma was made. Immunocytological investigations revealed strong reactivity of the TMC to antisera against vimentin, common leucocyte antigen (CLA), alpha 1-antitrypsin (alpha 1-AT) and alpha 1-antichymotrypsin (alpha 1-ACT). A minor proportion of the TMC reacted to antisera against lysozyme and KiB3. Surprisingly, the TMC also reacted to antisera against certain regulatory peptides (RP), namely adrenocorticotropic hormone (ACTH), peptide histidine isoleucine (PHI), leu-enkephalin and met-enkephalin. However, absorption controls revealed that the immunostaining for ACTH and the two enkephalins was non-specific. The immunocytological phenotype of TMC suggests a close relationship to the myeloid-monocytic lineage, but a possible relationship between TMC and the diffuse neuroendocrine system needs further investigation.

show abstract

Structural and Biochemical Characteristics of Mast Cells

Bloom¹

1974

The Inflammatory Process

View full text Add to dashboard Cite

Solitary Mastocytoma

Cited by 6 publications

References 26 publications

A blistering plaque on the palm of an infant

A blistering plaque on the palm of an infant

Solitary mastocytoma of the eyelid

Structural and Biochemical Characteristics of Mast Cells

Contact Info

Product

Resources

About