Solitary Hard Nodule on the Forearm

Abstract

A 57-year-old man presented with a 2-year history of a slowly enlarging, asymptomatic nodule on the right forearm. There was no history of trauma to the area, and the patient's medical history was otherwise insignificant.Physical examination disclosed a 2.0 X 2.5-cm, erythematous, hard, freely mobile, elevated nodule on the anterior aspect of the proximal right forearm (Fig 1). No lymphadenopathy was present. The remainder of the physical examination was normal.Representative sections of an excisional biopsy specimen are shown (Figs 2 and 3).What is your diagnosis? Figure 1.Figure 2.Figure 3.Clinicians, local and regional societies, and residents and fellows in dermatology are invited to submit quiz cases to this section. Cases should follow the established pattern and be submitted double-spaced and in triplicate. Photomicrographs and illustrations must be clear and submitted as positive color transparencies (35 mm). Do not submit color prints unless accompanied by original transparencies. If photomicrographs are not available, the actual slide from the specimen will be acceptable.

Pilomatricoma in Children: A Prospective Study

“…A minority of individuals have more than one lesion, as in many benign skin appendaged tumors. Multiple pilomatricomas may occur in associated syndromes such a.s myotonic dystrophy and Gardner .syndrome (1)(2)(3)(4)(5). The clinical features of the pilomatricomas in our series are presented and discussed in this article.…”

Pilomatrixoma-A Case Report

“…These tumours are commonly present in the head and neck region but occurrence in other parts of the body has also been reported. These tumors are most common in 0-20 years of age group [6,9,10]. Pilomatrixoma presents usually as a single asymptomatic nodule.…”

“…Pilomatrixoma presents usually as a single asymptomatic nodule. The skin over the tumour is mostly normal but occasionally may have a reddish or bluish discoloration [10]. These tumours are well circumscribed ovoid or spherical in shape and sometimes it may be encapsulated [9,10].…”

“…The skin over the tumour is mostly normal but occasionally may have a reddish or bluish discoloration [10]. These tumours are well circumscribed ovoid or spherical in shape and sometimes it may be encapsulated [9,10]. Multiple tumours are associated with Gardner syndrome, Turner syndrome, myotonic dystrophy,sarcoidosis and Steinert disease [6].…”

Pilometrixoma of the Thigh - A Case Report

“…Although it can occur at any age most cases of pilomatrixoma occur in children. It is most common on the head, face and neck, but lesions can also occur on the upper and lower extremities and trunk 3 and are rarely reported in other sites 4 . Pilomatrixoma is associated with high levels of beta-catenin caused by either a mutation in the APC gene or beta-catenin gene.…”