Solitary giant molluscum contagiosum presenting as lid tumor in an immunocompetent child

Abstract

We report the case of a three-year-old male child who presented with a single painless subcutaneously located upper lid mass of 1.2 × 1.5 cm with a central depression. The mass could be easily separated from overlying skin on complete excision biopsy and showed a never described before whitish brain like appearance consisting of multiple lobes and gyri, which histopathologically proved to be molluscum contagiosum (MC). Tests to investigate underlying immunodeficiency did not show any evidence of immunocompromised state.

Göz Kapağında Yoğun Molluskum Kontagiosumu Olan Immunokompetan Çocuğun Sadece Fiziksel Boşaltma Yolu ile Tedavisi

“…7,10 Chemical agents such as silver nitrate, phenol and trichloroacetic acid, in resistant lesions in immunocompromised patients topical antiviral agent cidofovir (5%), intralesional or systemic interferon alpha, imiquimod (5%) cream, salicylic acid, glycolic acid, tretinoin, tazortene, 5% sodium nitrite co-applied daily with 5% salicylic acid topical preparations, podofilox, liquefied phenol, tretinoin, cantharidin, potassium hydroxide, adapelene 1% cream have been reported. 5,7,10 Oral treatment with cimetidine is another option. 7,10 A review of Cochrane database including 495 cases indicated that no therapy was universally and convincingly effective in treatment of MC.…”

“…For faster resolution, many treatment modalities such as cryotherapy, extirpation and cauterization of base, topical chemical and antiviral agents, and oral cimetidine have been used. [3][4][5] …”

Treatment of Molluscum Contagiosum in Adult, Pediatric, and Immunodeficient Populations

“…52 The most common treatment for ocular and periocular molluscum infections is surgical excision of the lesions, which has generally led to rapid and dramatic resolution of the disease. [52][53][54] The concurrent conjunctivitis has been frequently observed to resolve simultaneously with the clearance of the molluscum lesions, which provides further evidence that conjunctivitis occurs as a secondary disease. 52 …”

Molluscum contagiosum simulating a sebaceous cyst: a rare presentation

“…Giant MC with atypical sites such as the eyelid and nipple. 5,12,13 Though MCV affects any group, children are found to be more commonly affected by this virus.…”