Solitary fibrous tumor/hemangiopericytoma of the penis

Abstract

Solitary fibrous tumor/hemangiopericytoma (SFT-HMP) is a rare spindle-cell mesenchymal tumor, thought to be of myofibroblastic origin. Penile SFT-HMP was mentioned in the literature in two separate case reports which were published in 2015 and 2017. We present the first case of SFT-HMP which is localized on corpus cavernosum of the penis. A 55-year-old man presented to our clinic with a small and gradually growing lesion on his penis for the past year, which recently caused difficulties during sexual intercourse. On physical examination; a well-shaped, nodular non-fluctuant, solid, painless mass, measuring 4x4 cm was palpated. Magnetic resonance imaging showed 5x5 cm mass located on the right corpus cavernosa. Under spinal anesthesia, surgical excision was performed. Pathologically, the tumor had an irregular architecture patterns and was characterized by hypercellular areas separated by thin-walled, branching vessels, lined with a single layer of flattened endothelial cells. SFT-HMP rarely occurs in genital tract and penile presentation is among the rarest. It should be classified and considered under penile masses, especially if the mass is well circumscribed, painless and slowly growing in nature. After differential diagnosis, surgical excision is mandatory.

Malignant solitary fibrous tumor of the penis: A case report of rare malignancy

“…Cubuk et al added CD99 and bcl2 markers which also revealed diffuse and strong positivity. 3 , 4 Similarly, immunohistochemical staining on CD34 and vimentin revealed a diffuse positive result in our case.…”

“…The last report from Castellani and Cubuk does not reveal the medical and surgical history of SFT of the penis. 3 , 4 No records of promiscuity were found in our case and other case reports. Meanwhile, our patient reported prior trauma when he was eight years old.…”

“… 2 Castellani et al reported that their patient was a 44-year-old man, meanwhile, Cubuk et al reported a 55-year-old man complaining of a small, gradually growing lesion on his penis. 3 , 4 In our case, the patient reported the first complaint when he was eight years old. Then, the tumor enlarged slowly after his marriage nine years ago.…”

“… 1 However, there is no local recurrence nor distant metastasis found from the latest report of penile SFT. 3 , 4 …”

A Rare Case of Solitary Fibrous Tumour of the Pelvis in an 18-Year-Old Young Man: CT and MRI Features with Pathologic Correlations

“…1 While SFTs were originally thought to be exclusively located in the pleura, the pericardium, or the peritoneum, recent studies have shown that they can occur anywhere in the body. [2][3][4][5][6] SFT manifests as a slow growing, often asymptomatic mass which affects middleaged adults regardless of gender. Symptoms include pain, neurologic or vascular alterations.…”