Solitary fibrous tumor

Yilmaz, Cem; Kabataş, Serdar; Özen, Özlem; Gülşen, Salih; Caner, Hakan; Altınörs, Nur

doi:10.1016/j.jocn.2009.02.039

Cited by 24 publications

(13 citation statements)

References 24 publications

(29 reference statements)

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“…[3] Meningiomas, schwannomas and HPC need to be considered in the differential diagnosis. [6] Formation of psammoma bodies and nuclear pseudo inclusions may be seen rarely in SFT. [7] Meningiomas are usually stained with EMA and/or S-100 protein whereas SFT are not stained with these.…”

Section: Discussionmentioning

confidence: 99%

Solitary fibrous tumor of the cerebellopontine angle: A case report and literature review

Chandran¹,

Prabhakar²,

Peethambaran³

et al. 2017

IJNS

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118revealed a normal higher mental function with a gaze-evoked nystagmus to the right and profound sensori-neural hearing loss on the same side. He had right-sided cerebellar signs, House-Brackmann (HB) grade 2 facial palsy and no neurocutaneous markers or enlarged lymph nodes.Magnetic resonance imaging (MRI) brain showed a T2 heterogeneously hyperintense extra-axial lesion, measuring 4.5 × 3.5 × 3 cm in the right CP angle with solid and cystic areas. The lesion showed intense enhancement on contrast administration and pressure effect on pons, with no extension to internal auditory canal [ Figure 1]. There was evidence of obstructive hydrocephalus. A preoperative diagnosis of CP angle meningioma was made, and preoperative embolization was planned. Digital subtraction angiography revealed dense tumor blush with predominant arterial feeders from vertebro-basilar system and small branches from right external carotid artery (ECA) [ Figure 2]. Embolization was not carried out as the predominant supply was from intracranial arteries, and the ECA feeders were too small to cannulate.Right suboccipital retrosigmoid craniectomy was done. The tumor was reddish in color and highly vascular. It was soft in consistency, with no definite plane with surrounding normal parenchyma; and was adherent to the petrous ridge and to the tentorium cerebelli. Facial nerve was found antero-superior to the tumor.

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Section: Discussionmentioning

confidence: 99%

Solitary fibrous tumor of the cerebellopontine angle: A case report and literature review

Chandran¹,

Prabhakar²,

Peethambaran³

et al. 2017

IJNS

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“…These findings are similar to those of myofibroblastoma. However, unlike for myofibroblastoma, branching hemangiopericytoma-like vessels and rare mitotic figures are characteristics that are also present (12,13). Immunohistochemical analysis has shown that SFTs are strongly and diffusely positive for CD34, vimentin, B-cell lymphoma-2 and CD99, but negative for SMA, EMA or S-100 protein (14–17).…”

Section: Discussionmentioning

confidence: 99%

Meningeal myofibroblastoma in the frontal lobe: A case report

Xu¹,

Feng²,

Wu³

et al. 2014

Oncology Letters

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Myofibroblastoma is a benign tumor composed of spindle cells in clusters and fascicles. To date, only three cases of intracranial myofibroblastoma have been reported. The present study reports the case of a 47-year-old female with meningeal myofibroblastoma. The patient had a history of ovarian cyst resection and presented with paroxysmal mild headaches that had been apparent for 4 years. Magnetic resonance imaging disclosed a well-circumscribed mass in the left frontal lobe. A resection of the mass was performed. Abundant fascicular clusters of spindle- and oval-shaped cells were found by conventional histopathology. Immunohistochemical staining demonstrated that these cells were strongly positive for smooth muscle actin, weakly positive for epithelial membrane antigen and negative for cluster of differentiation (CD)117, CD34, S-100 or desmin, with a Ki-67 index of >10%. These results supported the diagnosis of myofibroblastoma. No recurrence of the mass was found during the 24-month follow-up period. Overall, the patient exhibited a rare type of meningeal neoplasm. Resection of the tumor proved to be successful and no recurrence were found. Histopathological and immunohistochemical staining is crucial to form a diagnosis. To the best of our knowledge, the present study is the first to show the presence of myofibroblastoma in the left frontal lobe.

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“…Since then, few cases of mSFT have been reported in both cranial and spinal compartments [4]. Spinal mSFT can arise in the entire spine and accounts for 25% of all mSFT [1] but rarely occurs in the lumbar area (<12%) [9].…”

Section: Discussionmentioning

confidence: 99%

“…The latter location remains particularly rare with few cases of meningeal SFT (mSFT) reported in the literature [4] and fewer cases of the lumbar spine are even reported. We herein report the fifth case of solitary fibrous of the lumbar spine.…”

Section: Introductionmentioning

confidence: 99%