Solitary extramedullary plasmacytoma of the upper respiratory and digestive tracts

Less than 10% of the patients with plasma cell neoplasms present with a solitary plasmacytoma. Though the nasal cavity is a common extramedullary site, the occurrence is extremely rare. Two cases of solitary extramedullary plasmacytoma of the sinonasal region are reported. The first of which is sinonasal plasmacytoma with concomitant HIV, an association that has been reported rarely in literature to date and is matter of much debate. In the second case report, we present an instance of surgical excision of the tumor using KTP 532 laser. The diagnosis was established using immunohistochemical techniques and multiple myeloma workups were negative in all cases.

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“…Cervical lymphadenopathy has been noted in 20-25% of head and neck solitary plasmacytomas [6]. The diagnosis is usually as a result of biopsy.…”

Section: Discussionmentioning

confidence: 99%

Solitary Extramedullary Plasmacytoma of the Sinonasal Region

Hazarika

Balakrishnan

Singh

et al. 2011

Indian J Otolaryngol Head Neck Surg

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“…9,11,12 The clinical presentation varies according to the involved organ. 13 EMP of larynx may present with hoarseness of voice or dysphagia. 8 Cervical node metastasis and acute laryngeal obstruction have been reported.…”

Section: Discussionmentioning

confidence: 99%

Plasmacytoma Of Larynx—A Case Report

et al. 2009

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“…They occur more frequently in men than women and 75% of the tumors occur during the sixth decade of life (9, 10). More than 90% of these tumors grow in the head and neck area, with 75% originating in the nasal cavity and paranasal sinuses (11).…”

Section: Discussionmentioning

confidence: 99%

Solitary extramedullary plasmacytoma arising in the pterygoid fossa

Halefoğlu

2004

Acta Oto-Laryngologica

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A case of solitary extramedullary plasmacytoma of the left pterygoid fossa is presented, which is an unusual location for such tumors. A 54-year-old male patient was admitted for retro-orbital and left-sided facial pain which had persisted for several months. Physical, nasal endoscopic and optic examinations showed no abnormalities. No palpable cervical lymph nodes were found. MRI revealed a 2-cm mass in the left pterygoid fossa. A biopsy was carried out and the resulting histological evaluation of the mass confirmed a plasmacytoma. A comprehensive work-up, including bone marrow biopsy, total-body skeletal survey, technetium scintigrams, determination of urine Bence-Jones protein and serum myeloma protein, chest radiograph, total blood count and urinalysis, was carried out in order to rule out multiple myeloma. All of these studies were unremarkable in terms of a systemic disease and therefore the patient was diagnosed as having a solitary extramedullary plasmacytoma of the pterygoid fossa. He was referred for radiation therapy, receiving irradiation of 50 Gy for 6 weeks. The clinical manifestations, imaging findings, pathology and treatment procedures of extramedullary plasmacytoma are described, together with a review of the literature.

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Solitary extramedullary plasmacytoma of the upper respiratory and digestive tracts

Cited by 53 publications

References 13 publications

Solitary Extramedullary Plasmacytoma of the Sinonasal Region

Solitary Extramedullary Plasmacytoma of the Sinonasal Region

Plasmacytoma Of Larynx—A Case Report

Solitary extramedullary plasmacytoma arising in the pterygoid fossa

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