Solitary Colonic Metastasis of Renal Cell Carcinoma

Abstract

We report a rare case of a solitary metastasis of a renal cell carcinoma which manifested as a primary colonic tumour. A 60-year-old male patient who had undergone a right radical nephrectomy 5 years previously for renal cell carcinoma, presented with a history of dyspepsia and pain in the right upper abdomen. A mass on the hepatic flexure was detected by computed tomography and colonoscopy and right hemicolectomy was performed. Postoperative histological examination revealed that the tumour was a metastatic renal cell carcinoma of the clear cell type.

Thyroid Metastasis of Renal Cell Carcinoma

“…Moreover, metastases to the thyroid, soft tissue, colon, muscle and any other organ can be found. 6,7 In our present case, renal tumor had been detected incidentally. After right radical nephrectomy, RCC had been showed on histological examination.…”

Metastatic Clear Cell Renal Cell Carcinoma Presenting as Multiple Colonic Polyps

“…8,9 The large bowel appears to be the least common site of GIT involvement by metastatic renal cell carcinoma and only sporadic case reports exist. [10][11][12][13][14][15][16] There has been a single-case report of a sarcomatoid variant of renal cell carcinoma metastasizing to the sigmoid colon. 17 In addition, metastatic renal cell carcinoma of the clear cell variety have presented as hemorrhoids in the anal canal.…”

“…The periods after nephrectomy tended to be long: 11, 17, 9, 7, 4, 5, and 5.5 years, respectively. [10][11][12][13][14][15][16] If the current case is included, then the average time after nephrectomy for the occurrence of the colonic metastasis is 9.4 years. In contrast to all the cases reported so far, the patient described in this report presented with multiple, small polypoid lesions that were asymptomatic.…”

Solitary colonic metastasis from renal cell carcinoma presenting as a surgical emergency nine years post-nephrectomy

“…84% of these were within the first five years following surgery. Late recurrence of RCC occurs in as many as 11% of patients surviving ten years or more, and the longest reported interval from nephrectomy to recurrence is 31 years [7,9,10]. …”