Solitary Atypical Adenomatous Hyperplasia in the Lung of a 17-Year-Old Man with Spontaneous Pneumothorax

Abstract

We report here a case of solitary atypical adenomatous hyperplasia (AAH). A 17-year-old non-smoker man developed spontaneous pneumothorax, and computed tomogram scanning of his chest revealed a ground-glass opacity measuring 5 × 5 mm in the right lung with no change in its size for the next 7 months. To exclude the possibility of pulmonary neoplasia, he underwent partial pulmonary resection. The postoperative pathologic diagnosis was AAH. The present case is very exceptional for AAH because of the patient’s young age and non-association with pulmonary carcinoma. The postoperative 23-month follow-up was uneventful.

Solitary Atypical Adenomatous Hyperplasia in a 12-Year-Old Girl

“…However, the number of reported cases is very small and no cases of solitary AAH in a child have been reported. The youngest case of solitary AAH was a 17-year-old male in Japan, reported in 2003 [ 7 ].…”

Exuberant type 2 pneumocyte hyperplasia: mimic or forerunner of atypical adenomatous hyperplasia?

“…The authors argued its benign nature, mimicking pre‐invasive cancerous lesions of the lung. Conversely, atypical adenomatous hypeplasia (AAH) is well known, and there is a convergence of views that support its precursor role towards lung adenocarcinoma . Recently, we have evaluated the case of a 30‐year‐old Tunisian man, an active smoker, who was admitted to the emergency room for a spontaneous pneumothorax in the superior apex of the left lung.…”