Solitary Angiokeratoma Seen in a Patient with Pretibial Epidermolysis Bullosa

Maeda, Manabu

doi:10.1111/j.1346-8138.1987.tb03005.x

Cited by 5 publications

(1 citation statement)

References 9 publications

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“…AKs secondary to process with lymphatic obstruction, mainly scars, may appear. In this manner, AK type lesions related to bullous epidermolysis scars [66] , sclerodermatous graft versus host disease [67] or lichen sclerosus [68] (Figure 11) have been described. Figure 11 Figure 12 Angiokeratoma-like changes in lichen sclerosus represent secondary features because of damage to the dermis by lichen sclerosus and are characterized histologically by ectatic thinwalled vascular spaces in the papillary dermis intimately associated with the epidermis.…”

Section: Ak Secondary To Other Process With Lymphatic Obstructionmentioning

confidence: 95%

Differential Diagnoses of Angiokeratomas

2020

AJODRR

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Review Article AJODRR (2020) 3:34 DIFERENTIAL DIAGNOSES OF ANGIOKERATOMAS Angiokeratomas (AK) are probably the vascular lesions that induce more confusion in the literature. The most accepted classification of AK was performed by Imperial and Helwig [1] , and they divide these lesions into five classical types: Mibelli's AK, Fordyce's AK, corporis diffusum AK, circumscribed naeviforme AK and solitary or multiple adquired angiokeratomas. Nevertheless, in the clinical practice, is not unusual to see AK type lesions associated to different types of vascular anomalies, and these lesions have difficult handling. In ISSVA classification AKs have been included as vascular anomalies provisionally unclassified. We perform the differential diagnoses of AKs and according to clinical picture, histopathological aspect, immunohistochemical markers and radiological findings proposed to divide AKs mainly in two groups. Primary AKs are the classical types. The new inmunohistochemical findings suggest that these lesions might be included as mixed capillary-lymphatic malformations. Secondary AKs are related with different vascular anomalies, secondary to other process with lymphatic obstruction, related to drugs, or associated with no vascular lesions as lymphoid lesions. Different underlying vascular anomelies might be related with AKs including deep capillary-lymphatic malformations (CLM), venous-lymphatic malformations (VLM), capillary-lymphatic-venous malformations (CLVM) (Klippel-Trenaunauy Sd), deep lymphatic malformations (LM), venous malformations (VM) as hyperkeratotic venous malformation, cavenomatous cerebral malformations, traumatic arteriovenous fistula and eccrine angiokeratomatous hamartoma. Clinical aspect, radiological studies and histopathological examination might help to do a correct diagnosis of this heterogenous entity.

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Section: Ak Secondary To Other Process With Lymphatic Obstructionmentioning

confidence: 95%