Solid-Supported Catalysts for Atom-Transfer Radical Cyclization of 2-Haloacetamides

1-[(4-Methylphenyl)sulfonyl]pyrrolidin-2-one

“…The molecular dimensions in (I) are in agreement with the corresponding distances reported for a few structures containing a phenylsulfonylpyrrolidin-2-one fragment in the Cambridge Structural Database (Version 5.27;Allen, 2002), e.g. refcodes GUBNOG (Iwamatsu et al, 1999), JIRKOK and JIRLAX (Amato et al, 1990), KONJAY (Bandoli et al, 1992), QACQUH (Benerjee et al, 2002), QELJUM (Clark et al, 1999), SOVDOW and SOVDUC (Amato et al, 1991), and WEPDOK (Taksukawa et al, 1993).…”

Atom‐Transfer Radical Addition (ATRA) and Cyclization (ATRC) Reactions Catalyzed by a Mixture of [RuCl2Cp*(PPh3)] and Magnesium

“…All spectra were recorded at room temperature. N ‐Allyl‐ N ‐4‐toluenesulfonyl‐2,2‐dichloroacetamide ( 8 ),33 N ‐benzyl‐2‐methyl‐2‐bromo‐ N ‐cyclohexyl‐1‐enylpropionamide ( 9 ),23b [(2,2,2‐trichloroethoxy)prop‐1‐enyl]benzene ( 10 ),22b hex‐5‐enyl‐2,2‐dichloroacetate ( 11 ),28 and 2‐(allyloxy)ethyl‐2,2,2‐trichloroacetate ( 12 )29 were prepared according to literature procedures.…”

Stereo/regio-controlled cyclization of polychlorohex-5-enoic acids into substituted cyclobutanes

“…The development of new available synthesis procedures for these rings and the study of the regio-and stereochemistry of these processes are extremely important tasks. From the practical viewpoint it is signifi cant to search for new possibilities of ATRC application, especially taking into account the more and more growing number of developed highly active catalytic systems [ 5,8,9]. The reactions of trichloroacetic acid derivatives with various alka-1,3-dienes under the ATRA conditions are known to result in the formation of the corresponding α,α-dichloroalkenoic acids or alkenyl-substituted α,α-dichloro-γ-lactones [10][11][12].…”