Solid-state inorganic and metallic adhesives for soft biological tissues

Okada, Masahiro; Matsumoto, Takuya

doi:10.1016/j.jdsr.2023.11.003

Cited by 1 publication

(1 citation statement)

References 76 publications

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“…Recently, we showed that porous HAp [16] and OCP [17] plates could be used as solid-state adhesives for wet soft tissues. [18] Although these porous solid-state adhesives have potential use as adhesive liver retractors, there are no data on the adhesiveness of these solid-state adhesives on the liver. Furthermore, our previous report [16] revealed that water in the adherend was migrated (i.e., absorbed) into the HAp plate, and a condensed layer of organics was formed on the tissue surface contacting the HAp plate.…”

Section: Introductionmentioning

confidence: 99%

Water‐Mediated On‐Demand Detachable Solid‐State Adhesive of Porous Hydroxyapatite for Internal Organ Retractions

Okada,

Xie,

Kobayashi

et al. 2024

Adv Healthcare Materials

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Novel adhesives for biological tissues offer an advanced surgical approach. Here, we report the development and application of solid‐state adhesives consisting of porous hydroxyapatite (HAp) biocompatible ceramics as novel internal organ retractors. The operational principles of the porous solid‐state adhesives were experimentally established in terms of water migration from biological soft tissues into the pores of the adhesives, and their performance was evaluated on several soft tissues with different hydration states. As an example of practical medical utility, HAp adhesive devices demonstrated the holding ability of porcine livers and on‐demand detachability in vivo, showing great potential as internal organ retractors in laparoscopic surgery.This article is protected by copyright. All rights reserved

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