Solid phase synthesis of oligomeric guanidiniums

Crystal structure of 1,1,3,3-tetramethyl-2-(1,3-dimethylimidazolidin-2- yl)guanidinium chloride, (C10H24N5)Cl

“…Guanidinium compounds are of great interests mainly due to their high chemical and thermal stability, as well as catalytic activity [1][2][3]. Becauseo ft he unique role in molecular recognition, guanidiniumand its derivatives become one of the key subjects in life science research [4].…”

Guanidylated hollow fiber membranes based on brominated poly (2,6-dimethyl-1,4-phenylene oxide) (BPPO) for gold sorption from acid solutions

“…The IEC value was determined by the Mohr method. The HFMs were transformed to chloride (Cl − ) form first, and then the chloride ions were exchanged by sulfate ions (SO 4 2− ). The IEC value was calculated from the released chloride ions, which were determined by REX PHS-3C (China) with a Cl − ion-selective electrode (model pCl-1).…”

“…Therefore, guanidyl groups can conveniently form ion exchange interaction or complexation with different receptors [3], such as phosphate, carboxylate and metal ions. Among the varieties of guanidine compounds, polymers with guanidyl groups have deserved much attention, since they usually show unique separation performance or physiological activity [4].…”

Solid-Phase Synthesis of Quinazoline-2,4-Diones and Their Analogues from Resin-Bound Compounds with Primary Amines

“…Subsequent S-alkylation with alkylhalides 67 gave various S-substituted quinazoline-2-thioxo-4-ones 68 with high purity. Although S-alkylated thiourea usually reacts with various amines to give guanidines [17], these S-alkylated quinazoline-2-thioxo-4-ones 6 8 were found to be surprisingly stable, thus the attempts to convert these compounds into 2-aminoquinazolin-4-ones at high temperature were not successful.…”